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Description:
Single-stranded DNA-binding protein (SSB) (Helix-destabilizingprotein).
Molecular weight: 18943
View which proteins in this organism that is involved with DNA Repair;
classified after biological processes (using data from the GOA project):
DNA repair( GO:0006281 )
Important dates:
15-MAR-2005, integrated into UniProtKB/Swiss-Prot.
15-MAR-2005, sequence version 1.
07-MAR-2006, entry version 8.
Phylogenetic order:
Bacteria Proteobacteria Gammaproteobacteria Enterobacteriales Enterobacteriaceae Salmonella.
To calculate the pI (Isoelectric point - the pH where a protein has a neutral charge),
go to this page and enter the protein ID (e.g 3MG_ECOLI): http://us.expasy.org/tools/pi_tool.html
Links to references in other databases for protein SSB_SALTI:
| Database | Pointer | Add. info#1 | Add. info#2 |
| EMBL | AL627282 | CAD09239.1 | - |
| EMBL | AE014613 | AAO71625.1 | - |
| HSSP | P02339 | 1KAW | |
| SMR | P0A2F7 | 1-123.1 | |
| GenomeReviews | AL513382_GR | STY4451.1 | |
| GenomeReviews | AE014613_GR | t4161.1 | |
| InterPro | IPR012340 | OB_NA_bd_sub. | |
| InterPro | IPR011344 | Single_strand_bd. | |
| InterPro | IPR000424 | SSB_primosomal_n. | |
| InterPro | IPR010913 | ssDNA_bd. | |
| Pfam | PF00436 | SSB | 1. |
| TIGRFAMs | TIGR00621 | ssb | 1. |
| PROSITE | PS50935 | SSB | 1. |
Keywords:
Complete proteome; DNA damage; DNA repair; DNA replication; DNA-binding.
References:
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CT18;
RX MEDLINE=21534947; PubMed=11677608; DOI=10.1038/35101607;
RA Parkhill J., Dougan G., James K.D., Thomson N.R., Pickard D., Wain J.,
RA Churcher C.M., Mungall K.L., Bentley S.D., Holden M.T.G., Sebaihia M.,
RA Baker S., Basham D., Brooks K., Chillingworth T., Connerton P.,
RA Cronin A., Davis P., Davies R.M., Dowd L., White N., Farrar J.,
RA Feltwell T., Hamlin N., Haque A., Hien T.T., Holroyd S., Jagels K.,
RA Krogh A., Larsen T.S., Leather S., Moule S., O'Gaora P., Parry C.,
RA Quail M.A., Rutherford K.M., Simmonds M., Skelton J., Stevens K.,
RA Whitehead S., Barrell B.G.;
RT "Complete genome sequence of a multiple drug resistant Salmonella
RT enterica serovar Typhi CT18.";
RL Nature 413:848-852(2001).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Ty2 / ATCC 700931;
RX MEDLINE=22531367; PubMed=12644504;
RX DOI=10.1128/JB.185.7.2330-2337.2003;
RA Deng W., Liou S.-R., Plunkett G. III, Mayhew G.F., Rose D.J.,
RA Burland V., Kodoyianni V., Schwartz D.C., Blattner F.R.;
RT "Comparative genomics of Salmonella enterica serovar Typhi strains Ty2
RT and CT18.";
RL J. Bacteriol. 185:2330-2337(2003).
Feature:
INIT_MET 0 0 By similarity.
CHAIN 1 175 Single-stranded DNA-binding protein.
/FTId=PRO_0000096090.
DOMAIN 5 110 SSB.
DNA_BIND 54 60 By similarity.
Comments:
-!- FUNCTION: This protein is essential for replication of the
chromosomes and its single-stranded DNA phages. It is also
involved in DNA recombination and repair (By similarity).
-!- SUBUNIT: Homotetramer (By similarity).
-!- SIMILARITY: Contains 1 SSB domain.
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Sequence length: 175
ASRGVNKVIL VGNLGQDPEV RYMPSGGAVA NLTLATSESW RDKQTGEMKE QTEWHRVVMF
GKLAEVAGEY LRKGSQVYIE GQLRTRKWTD QSGQERYTTE INVPQIGGVM QMLGGRQGGG
APAGGQQQGG WGQPQQPQQP QGGNQFSGGA QSRPQQSAPA PSNEPPMDFD DDIPF