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Description:
Alkylated DNA repair protein alkB.
Molecular weight: 23787
View which proteins in this organism that is involved with DNA Repair;
classified after biological processes (using data from the GOA project):
DNA repair( GO:0006281 )
Important dates:
01-OCT-1994, integrated into UniProtKB/Swiss-Prot.
19-DEC-2001, sequence version 2.
07-MAR-2006, entry version 33.
Phylogenetic order:
Bacteria Proteobacteria Gammaproteobacteria Enterobacteriales Enterobacteriaceae Salmonella.
To calculate the pI (Isoelectric point - the pH where a protein has a neutral charge),
go to this page and enter the protein ID (e.g 3MG_ECOLI): http://us.expasy.org/tools/pi_tool.html
Links to references in other databases for protein ALKB_SALTY:
| Database | Pointer | Add. info#1 | Add. info#2 |
| EMBL | AE008801 | AAL21166.1 | - |
| EMBL | D90221 | NOT_ANNOTATED_CDS | |
| PIR | B39433 | B39433. | |
| GenomeReviews | AE006468_GR | STM2264.1 | |
| StyGene | SG10006 | alkB. | |
| BioCyc | STYP99287:STM2264-MONOMER | -.1 | |
| InterPro | IPR005123 | 2OG-FeII_Oase. | |
| Pfam | PF03171 | 2OG-FeII_Oxy | 1. |
Keywords:
Complete proteome; DNA damage; DNA repair.
References:
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=LT2 / SGSC1412 / ATCC 700720;
RX MEDLINE=21534948; PubMed=11677609; DOI=10.1038/35101614;
RA McClelland M., Sanderson K.E., Spieth J., Clifton S.W., Latreille P.,
RA Courtney L., Porwollik S., Ali J., Dante M., Du F., Hou S., Layman D.,
RA Leonard S., Nguyen C., Scott K., Holmes A., Grewal N., Mulvaney E.,
RA Ryan E., Sun H., Florea L., Miller W., Stoneking T., Nhan M.,
RA Waterston R., Wilson R.K.;
RT "Complete genome sequence of Salmonella enterica serovar Typhimurium
RT LT2.";
RL Nature 413:852-856(2001).
RN [2]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 1-24.
RX MEDLINE=91267928; PubMed=1904855;
RA Hakura A., Morimoto K., Sofuni T., Nohmi T.;
RT "Cloning and characterization of the Salmonella typhimurium ada gene,
RT which encodes O6-methylguanine-DNA methyltransferase.";
RL J. Bacteriol. 173:3663-3672(1991).
Feature:
CHAIN 1 216 Alkylated DNA repair protein alkB.
/FTId=PRO_0000066666.
CONFLICT 19 19 A -> R (in Ref. 2).
Comments:
-!- FUNCTION: Probably involved in the repair of alkylated DNA.
-!- SIMILARITY: Belongs to the alkB family.
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Sequence length: 216
MLDLFADEAP WQEPLAPGAV VLRRFAFRAA QSLLDDIGFV ASQSPFRQMV TPGGYTMSVA
MTNCGALGWT TDRHGYCYAV RDPLTDKPWP ALPLSFASVC RQAAIAAGYA SFQPDACLIN
RYAPGAKLSL HQDKDEPDLR APIVSVSLGV PAVFQFGGLR RSDPIQRILL EHGDIVVWGG
ESRLFYHGIQ PLKAGFHPMT GEFRYNLTFR QAAEKE