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Description:
DNA repair protein radA (DNA repair protein sms).
Molecular weight: 49426
View which proteins in this organism that is involved with DNA Repair;
classified after biological processes (using data from the GOA project):
DNA repair( GO:0006281 )
Important dates:
01-MAR-1992, integrated into UniProtKB/Swiss-Prot.
13-DEC-2001, sequence version 3.
07-MAR-2006, entry version 46.
Phylogenetic order:
Bacteria Proteobacteria Gammaproteobacteria Enterobacteriales Enterobacteriaceae Salmonella.
To calculate the pI (Isoelectric point - the pH where a protein has a neutral charge),
go to this page and enter the protein ID (e.g 3MG_ECOLI): http://us.expasy.org/tools/pi_tool.html
Links to references in other databases for protein RADA_SALTY:
| Database | Pointer | Add. info#1 | Add. info#2 |
| EMBL | AE008915 | AAL23394.1 | - |
| EMBL | M85181 | NOT_ANNOTATED_CDS | |
| GenomeReviews | AE006468_GR | STM4579.1 | |
| StyGene | SG10444 | radA. | |
| BioCyc | STYP99287:STM4579-MONOMER | -.1 | |
| InterPro | IPR003593 | AAA_ATPase. | |
| InterPro | IPR001984 | Peptidase_S16. | |
| InterPro | IPR004504 | RadA. | |
| InterPro | IPR001553 | RecA_bac. | |
| PRINTS | PR01874 | DNAREPAIRADA. | |
| PRINTS | PR00830 | ENDOLAPTASE. | |
| SMART | SM00382 | AAA | 1. |
| TIGRFAMs | TIGR00416 | sms | 1. |
| PROSITE | PS50162 | RECA_2 | 1. |
Keywords:
ATP-binding; Complete proteome; DNA damage; DNA repair; DNA-binding; Metal-binding; Nucleotide-binding; Zinc; Zinc-finger.
References:
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=LT2 / SGSC1412 / ATCC 700720;
RX MEDLINE=21534948; PubMed=11677609; DOI=10.1038/35101614;
RA McClelland M., Sanderson K.E., Spieth J., Clifton S.W., Latreille P.,
RA Courtney L., Porwollik S., Ali J., Dante M., Du F., Hou S., Layman D.,
RA Leonard S., Nguyen C., Scott K., Holmes A., Grewal N., Mulvaney E.,
RA Ryan E., Sun H., Florea L., Miller W., Stoneking T., Nhan M.,
RA Waterston R., Wilson R.K.;
RT "Complete genome sequence of Salmonella enterica serovar Typhimurium
RT LT2.";
RL Nature 413:852-856(2001).
RN [2]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 163-460.
RC STRAIN=LT2;
RX MEDLINE=90330519; PubMed=2198247;
RA Foster J.W., Park Y.K., Penfound T., Fenger T., Spector M.P.;
RT "Regulation of NAD metabolism in Salmonella typhimurium: molecular
RT sequence analysis of the bifunctional nadR regulator and the nadA-pnuC
RT operon.";
RL J. Bacteriol. 172:4187-4196(1990).
Feature:
CHAIN 1 460 DNA repair protein radA.
/FTId=PRO_0000187937.
ZN_FING 11 28 C4-type (Potential).
NP_BIND 102 109 ATP (Potential).
Comments:
-!- FUNCTION: May play a role in the repair of endogenous alkylation
damage.
-!- SIMILARITY: Belongs to the recA family. RadA subfamily.
-!- CAUTION: Ref.2 sequence differs from that shown due to a
frameshift in position 271.
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Sequence length: 460
MAKAPKRAFV CNECGADYPR WQGQCSACHA WNTITEVRLA ASPTVARNER LSGYAGSAGV
SKVQKLSDIS LEELPRFSTG FKEFDRVLGG GVVPGSAILI GGNPGAGKST LLLQTLCKLA
EQMKTLYVTG EESLQQVAMR AHRLGLPTAN LNMLSETSIE QICLIAEEEQ PKLMVIDSIQ
VMHMADIQSS PGSVAQVRET AAYLTRFAKT RGVAIVMVGH VTKDGSLAGP KVLEHCIDCS
VLLDGDADSR FRTLRSHKNR FGAVNELGVF AMTEQGLREV SNPSAIFLSR GDEVTSGSSV
MVVWEGTRPL LVEIQALVDH SMMANPRRVA VGLEQNRLAI LLAVLHRHGG LQMSDQDVFV
NVVGGVKVTE TSADLALLLA MVSSLRDRPL PQDLVVFGEV GLAGEIRPVP SGQERISEAA
KHGFRRAIVP AANVPKKPPE GMLVFGVKKL ADALSVFDDL