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Description:
Single-stranded-DNA-specific exonuclease recJ (EC 3.1.-.-).
Molecular weight: 63367
View which proteins in this organism that is involved with DNA Repair;
classified after biological processes (using data from the GOA project):
DNA repair( GO:0006281 )
Important dates:
01-DEC-1992, integrated into UniProtKB/Swiss-Prot.
13-DEC-2001, sequence version 2.
07-MAR-2006, entry version 30.
Phylogenetic order:
Bacteria Proteobacteria Gammaproteobacteria Enterobacteriales Enterobacteriaceae Salmonella.
To calculate the pI (Isoelectric point - the pH where a protein has a neutral charge),
go to this page and enter the protein ID (e.g 3MG_ECOLI): http://us.expasy.org/tools/pi_tool.html
Links to references in other databases for protein RECJ_SALTY:
| Database | Pointer | Add. info#1 | Add. info#2 |
| EMBL | AE008840 | AAL21917.1 | - |
| EMBL | M38590 | AAA72913.1 | - |
| HSSP | Q93R48 | 1IR6 | |
| GenomeReviews | AE006468_GR | STM3042.1 | |
| StyGene | SG10332 | recJ. | |
| BioCyc | STYP99287:STM3042-MONOMER | -.1 | |
| InterPro | IPR003156 | Pesterase_DHHA1. | |
| InterPro | IPR001667 | Pesterase_RecJ. | |
| InterPro | IPR004610 | RecJ. | |
| Pfam | PF01368 | DHH | 1. |
| Pfam | PF02272 | DHHA1 | 1. |
| TIGRFAMs | TIGR00644 | recJ | 1. |
Keywords:
Complete proteome; Exonuclease; Hydrolase; Nuclease.
References:
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=LT2 / SGSC1412 / ATCC 700720;
RX MEDLINE=21534948; PubMed=11677609; DOI=10.1038/35101614;
RA McClelland M., Sanderson K.E., Spieth J., Clifton S.W., Latreille P.,
RA Courtney L., Porwollik S., Ali J., Dante M., Du F., Hou S., Layman D.,
RA Leonard S., Nguyen C., Scott K., Holmes A., Grewal N., Mulvaney E.,
RA Ryan E., Sun H., Florea L., Miller W., Stoneking T., Nhan M.,
RA Waterston R., Wilson R.K.;
RT "Complete genome sequence of Salmonella enterica serovar Typhimurium
RT LT2.";
RL Nature 413:852-856(2001).
RN [2]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 564-577.
RC STRAIN=LT2;
RX MEDLINE=91046011; PubMed=2236050;
RA Kawakami K., Nakamura Y.;
RT "Autogenous suppression of an opal mutation in the gene encoding
RT peptide chain release factor 2.";
RL Proc. Natl. Acad. Sci. U.S.A. 87:8432-8436(1990).
Feature:
CHAIN 1 577 Single-stranded-DNA-specific exonuclease
recJ.
/FTId=PRO_0000097232.
Comments:
-!- FUNCTION: Single-stranded-DNA-specific exonuclease. Required for
many types of recombinational events, although the stringency of
the requirement for recJ appears to vary with the type of
recombinational event monitored and the other recombination gene
products which are available.
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Sequence length: 577
MKQQRQLRRR EADETAELPA DLPPLLRRLY ASRGVRSARE LERSVKGMLP WQQLSGIDNA
VEILYNAFRE GTRIIVVGDF DADGATSTAL SVLGMRALGC DNISYLVPNR FEDGYGLSPE
VVDQAKARGA QLIVTVDNGI SSHAGVAHAK TLGIPVIVTD HHLPGDTLPD AEAIINPNLR
DCEFPSKSLA GVGVAFYLML ALRTFLRDKG WFDERNIAPP NLAELLDLVA LGTVADVVPL
DANNRILTWQ GLSRIRAGKC RPGIKALLEI SNRDPQQLAA SDLGFALGPR LNAAGRLDDM
SVGVALLLCD NLGEARVLAS ELDALNQTRK EIEQGMQAEA LILCEKLERS SETLPGGLAM
YHPEWHQGVV GILASRIKER FHRPVIAFAP AGDGTLKGSG RSIQGLHMRD ALERLDTLYP
DLMIKFGGHA MAAGLSLEEH KFEQFQQRFG ELVTEWLDPA LLQGEVISDG PLSAAEMSME
VAQLLRDAGP WGQMFPEPLF DGRFRLLQQR LVGERHLKVM VEPVGGGPLL DGIAFNIDTT
CWPDNGVREV ELAYKLDINE FRGNRSLQII IDDIWPL