Description:
Single-stranded DNA-binding protein (SSB) (Helix-destabilizingprotein).
Molecular weight: 18844
View which proteins in this organism that is involved with DNA Repair;
classified after biological processes (using data from the GOA project):
DNA repair( GO:0006281 )
Important dates:
21-JUL-1986, integrated into UniProtKB/Swiss-Prot.
20-DEC-2005, sequence version 1.
07-MAR-2006, entry version 5.
Phylogenetic order:
Bacteria Proteobacteria Gammaproteobacteria Enterobacteriales Enterobacteriaceae Shigella.
To calculate the pI (Isoelectric point - the pH where a protein has a neutral charge),
go to this page and enter the protein ID (e.g 3MG_ECOLI): http://us.expasy.org/tools/pi_tool.html
Links to references in other databases for protein SSB_SHIFL:
| Database | Pointer | Add. info#1 | Add. info#2 |
| EMBL | AE005674 | AAN45567.1 | ALT_INIT |
| EMBL | AE016989 | AAP18630.1 | - |
| GenomeReviews | AE014073_GR | S3584.1 | |
| GenomeReviews | AE005674_GR | SF4145.1 | |
| PROSITE | PS50935 | SSB | 1. |
Keywords:
Complete proteome; DNA damage; DNA repair; DNA replication; DNA-binding.
References:
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=301 / Serotype 2a;
RX MEDLINE=22272406; PubMed=12384590; DOI=10.1093/nar/gkf566;
RA Jin Q., Yuan Z., Xu J., Wang Y., Shen Y., Lu W., Wang J., Liu H.,
RA Yang J., Yang F., Zhang X., Zhang J., Yang G., Wu H., Qu D., Dong J.,
RA Sun L., Xue Y., Zhao A., Gao Y., Zhu J., Kan B., Ding K., Chen S.,
RA Cheng H., Yao Z., He B., Chen R., Ma D., Qiang B., Wen Y., Hou Y.,
RA Yu J.;
RT "Genome sequence of Shigella flexneri 2a: insights into pathogenicity
RT through comparison with genomes of Escherichia coli K12 and O157.";
RL Nucleic Acids Res. 30:4432-4441(2002).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=2457T / ATCC 700930 / Serotype 2a;
RX MEDLINE=22590274; PubMed=12704152;
RX DOI=10.1128/IAI.71.5.2775-2786.2003;
RA Wei J., Goldberg M.B., Burland V., Venkatesan M.M., Deng W.,
RA Fournier G., Mayhew G.F., Plunkett G. III, Rose D.J., Darling A.,
RA Mau B., Perna N.T., Payne S.M., Runyen-Janecky L.J., Zhou S.,
RA Schwartz D.C., Blattner F.R.;
RT "Complete genome sequence and comparative genomics of Shigella
RT flexneri serotype 2a strain 2457T.";
RL Infect. Immun. 71:2775-2786(2003).
Feature:
INIT_MET 0 0 By similarity.
CHAIN 1 177 Single-stranded DNA-binding protein.
/FTId=PRO_0000096039.
DOMAIN 5 110 SSB.
DNA_BIND 54 60 By similarity.
Comments:
-!- FUNCTION: This protein is essential for replication of the
chromosome. It is also involved in DNA recombination and repair
(By similarity).
-!- SUBUNIT: Homotetramer (By similarity).
-!- SIMILARITY: Contains 1 SSB domain.
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Sequence length: 177
ASRGVNKVIL VGNLGQDPEV RYMPNGGAVA NITLATSESW RDKATGEMKE QTEWHRVVLF
GKLAEVASEY LRKGSQVYIE GQLRTRKWTD QSGQDRYTTE VVVNVGGTMQ MLGGRQGGGA
PAGGNIGGGQ PQGGWGQPQQ PQGGNQFSGG AQSRPQQSAP AAPSNEPPMD FDDDIPF