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Description:
DNA repair protein radA homolog (DNA repair protein sms homolog).
Molecular weight: 49048
View which proteins in this organism that is involved with DNA Repair;
classified after biological processes (using data from the GOA project):
DNA repair( GO:0006281 )
Important dates:
30-MAY-2000, integrated into UniProtKB/Swiss-Prot.
01-AUG-1998, sequence version 1.
07-MAR-2006, entry version 43.
Phylogenetic order:
Bacteria Aquificae Aquificales Aquificaceae Aquifex.
To calculate the pI (Isoelectric point - the pH where a protein has a neutral charge),
go to this page and enter the protein ID (e.g 3MG_ECOLI): http://us.expasy.org/tools/pi_tool.html
Links to references in other databases for protein RADA_AQUAE:
| Database | Pointer | Add. info#1 | Add. info#2 |
| EMBL | AE000657 | AAC06790.1 | - |
| PIR | G70349 | G70349. | |
| HSSP | P03017 | 2REB | |
| GenomeReviews | AE000657_GR | AQ_552.1 | |
| BioCyc | AAEO63363:AQ_552-MONOMER | -.1 | |
| InterPro | IPR003593 | AAA_ATPase. | |
| InterPro | IPR007694 | DnaB_C. | |
| InterPro | IPR001984 | Peptidase_S16. | |
| InterPro | IPR004504 | RadA. | |
| InterPro | IPR001553 | RecA_bac. | |
| Pfam | PF03796 | DnaB_C | 1. |
| PRINTS | PR01874 | DNAREPAIRADA. | |
| PRINTS | PR00830 | ENDOLAPTASE. | |
| ProDom | PD332834 | DnaB_C | 1. |
| ProDom | PD000229 | RecA | 1. |
| SMART | SM00382 | AAA | 1. |
| TIGRFAMs | TIGR00416 | sms | 1. |
| PROSITE | PS50162 | RECA_2 | 1. |
Keywords:
ATP-binding; Complete proteome; DNA damage; DNA repair; DNA-binding; Metal-binding; Nucleotide-binding; Zinc; Zinc-finger.
References:
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=VF5;
RX MEDLINE=98196666; PubMed=9537320; DOI=10.1038/32831;
RA Deckert G., Warren P.V., Gaasterland T., Young W.G., Lenox A.L.,
RA Graham D.E., Overbeek R., Snead M.A., Keller M., Aujay M., Huber R.,
RA Feldman R.A., Short J.M., Olsen G.J., Swanson R.V.;
RT "The complete genome of the hyperthermophilic bacterium Aquifex
RT aeolicus.";
RL Nature 392:353-358(1998).
Feature:
CHAIN 1 444 DNA repair protein radA homolog.
/FTId=PRO_0000187919.
ZN_FING 10 27 C4-type (Potential).
NP_BIND 91 98 ATP (Potential).
Comments:
-!- FUNCTION: May play a role in the repair of endogenous alkylation
damage (By similarity).
-!- SIMILARITY: Belongs to the recA family. RadA subfamily.
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Sequence length: 444
MGKNKTAYVC QECGYKSVKW LGKCPSCGEW NTLVEEFEPQ SFSLVKKEPS LVLPVTDWEK
EEHERETTGF ESLDNALGGG LVKGQVILIA GEPGIGKSTL LLQISDRVAN GKKVLYVSGE
ESGTQIALRA KRLGINNENL LVYPEVNLEK ILQTLEKEKP SLLVLDSVQT IFSERLESSA
GSVSQVREVT YRITEFCKEK NVPAFIVGQI TKEGSIAGPK VLEHIVDTVL QFEGERFNFY
RIVKVIKNRF GSTGEIAVFK MTDKGLEEVP EPSAFFISEK ANAPGSVVFP HTEGSKPVLL
EVQALVIPAL YTTPQRRTQG FDPNRLALIL AVLEKEAKIF TRDQDVFVNV AGGMSVKEPA
ADLAVAMAVV SSKKEKEVPK DFVIFGEVGL SGEIRAVHFG DLRLKEAKRF GFKKALIPKS
LEIEIDGMEI YPVSHIQEAI EVLF