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Description:
Protein recA (Recombinase A).
Molecular weight: 37442
View which proteins in this organism that is involved with DNA Repair;
classified after biological processes (using data from the GOA project):
DNA repair( GO:0006281 )
Important dates:
30-MAY-2000, integrated into UniProtKB/Swiss-Prot.
01-AUG-1998, sequence version 1.
07-MAR-2006, entry version 38.
Phylogenetic order:
Bacteria Aquificae Aquificales Aquificaceae Aquifex.
To calculate the pI (Isoelectric point - the pH where a protein has a neutral charge),
go to this page and enter the protein ID (e.g 3MG_ECOLI): http://us.expasy.org/tools/pi_tool.html
Links to references in other databases for protein RECA_AQUAE:
| Database | Pointer | Add. info#1 | Add. info#2 |
| EMBL | AE000657 | AAC07868.1 | - |
| PIR | E70484 | E70484. | |
| HSSP | Q59560 | 1UBC | |
| GenomeReviews | AE000657_GR | AQ_2150.1 | |
| BioCyc | AAEO63363:AQ_2150-MONOMER | -.1 | |
| HAMAP | MF_00268 | - | 1. |
| InterPro | IPR003593 | AAA_ATPase. | |
| InterPro | IPR001553 | RecA_bac. | |
| Pfam | PF00154 | RecA | 1. |
| PRINTS | PR00142 | RECA. | |
| ProDom | PD000229 | RecA | 1. |
| SMART | SM00382 | AAA | 1. |
| TIGRFAMs | TIGR02012 | tigrfam_recA | 1. |
| PROSITE | PS00321 | RECA_1 | 1. |
| PROSITE | PS50162 | RECA_2 | 1. |
| PROSITE | PS50163 | RECA_3 | 1. |
Keywords:
ATP-binding; Complete proteome; DNA damage; DNA recombination; DNA repair; DNA-binding; Nucleotide-binding; SOS response.
References:
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=VF5;
RX MEDLINE=98196666; PubMed=9537320; DOI=10.1038/32831;
RA Deckert G., Warren P.V., Gaasterland T., Young W.G., Lenox A.L.,
RA Graham D.E., Overbeek R., Snead M.A., Keller M., Aujay M., Huber R.,
RA Feldman R.A., Short J.M., Olsen G.J., Swanson R.V.;
RT "The complete genome of the hyperthermophilic bacterium Aquifex
RT aeolicus.";
RL Nature 392:353-358(1998).
Feature:
CHAIN 1 345 Protein recA.
/FTId=PRO_0000122642.
NP_BIND 68 75 ATP (By similarity).
Comments:
-!- FUNCTION: Can catalyze the hydrolysis of ATP in the presence of
single-stranded DNA, the ATP-dependent uptake of single-stranded
DNA by duplex DNA, and the ATP-dependent hybridization of
homologous single-stranded DNAs. It interacts with lexA causing
its activation and leading to its autocatalytic cleavage.
-!- SUBCELLULAR LOCATION: Cytoplasm (By similarity).
-!- SIMILARITY: Belongs to the recA family.
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Sequence length: 345
MSENLSEKKK ALEVALSNIE KRFGKGAVMP LKSVEKVQVE TIPTGSLALD IATGVGGIPK
GRITEIFGVE SSGKTTLALH VIAEAQKRGG VAVFIDAEHA LDPKYAKKLG VDVENLYISQ
PDYGEQALEI AESLINSGAV DVIVVDSVAA LVPKDELEGE MGEAQVGKQA RLMSQALRKL
KGAVHKSNTA LIFINQIREK IGVMFGNPET TPGGRALKFF SDMRLEVRRL GDVKEGGEKK
GYRVKVRVVK NKLAPPFQEA EFDIIYGEGI CKLCDLIEVA TNLGIFTKSG SWYSYGDKRL
GQGKEQVKKY LQEHPELIDE IDQKVREAAG LAGSNIEEST GEEGK