Protein data for MUTS_NEIMA:

Description:
DNA mismatch repair protein mutS.

Molecular weight: 95249

View which proteins in this organism that is involved with DNA Repair;
classified after biological processes (using data from the GOA project):

DNA repair( GO:0006281 ) mismatch repair( GO:0006298 )


Important dates:
22-AUG-2003, integrated into UniProtKB/Swiss-Prot.
01-OCT-2000, sequence version 1.
07-MAR-2006, entry version 24.

Phylogenetic order:
Bacteria Proteobacteria Betaproteobacteria Neisseriales Neisseriaceae Neisseria.

To calculate the pI (Isoelectric point - the pH where a protein has a neutral charge),
go to this page and enter the protein ID (e.g 3MG_ECOLI): http://us.expasy.org/tools/pi_tool.html

Links to references in other databases for protein MUTS_NEIMA:

DatabasePointerAdd. info#1Add. info#2
EMBLAL162752CAB83555.1-
PIRC82019C82019.
HSSPP239091OH6
GenomeReviewsAL157959_GRNMA0247.1
BioCycNMEN65699:NMA0247-MONOMER-.1
HAMAPMF_00096-1.
InterProIPR005748MutS1.
InterProIPR000432MutS_C.
InterProIPR007860MutS_II.
InterProIPR007696MutS_III.
InterProIPR007861MutS_IV.
InterProIPR007695MutS_N.
PANTHERPTHR11361:SF23MutS.11.
PfamPF01624MutS_I1.
PfamPF05188MutS_II1.
PfamPF05192MutS_III1.
PfamPF05190MutS_IV1.
PfamPF00488MutS_V1.
ProDomPD001263MutS_C1.
SMARTSM00534MUTSac1.
SMARTSM00533MUTSd1.
TIGRFAMsTIGR01070mutS11.
PROSITEPS00486DNA_MISMATCH_REPAIR_21.

General information about the databases mentioned above

Keywords:
ATP-binding; Complete proteome; DNA damage; DNA repair; DNA-binding; Nucleotide-binding.

References:
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Z2491 / Serogroup A / Serotype 4A;
RX MEDLINE=20222556; PubMed=10761919; DOI=10.1038/35006655;
RA Parkhill J., Achtman M., James K.D., Bentley S.D., Churcher C.M.,
RA Klee S.R., Morelli G., Basham D., Brown D., Chillingworth T.,
RA Davies R.M., Davis P., Devlin K., Feltwell T., Hamlin N., Holroyd S.,
RA Jagels K., Leather S., Moule S., Mungall K.L., Quail M.A.,
RA Rajandream M.A., Rutherford K.M., Simmonds M., Skelton J.,
RA Whitehead S., Spratt B.G., Barrell B.G.;
RT "Complete DNA sequence of a serogroup A strain of Neisseria
RT meningitidis Z2491.";
RL Nature 404:502-506(2000).

Feature:
CHAIN 1 864 DNA mismatch repair protein mutS.
/FTId=PRO_0000115111.
NP_BIND 607 614 ATP (Potential).

Comments:
-!- FUNCTION: This protein is involved in the repair of mismatches in
DNA. It is possible that it carries out the mismatch recognition
step. This protein has a weak ATPase activity (By similarity).
-!- SIMILARITY: Belongs to the DNA mismatch repair mutS family.
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Sequence length: 864

     MSKSAVSPMM QQYLGIKAQH TDKLVFYRMG DFYEMFFDDA VEAAKLLDIT LTTRGQVDGE
     PVKMAGVPFH AAEQYLARLV KLGKSVAICE QVGEVGAGKG PVERKVVRIV TPGTLTDSAL
     LEDKETNRIV AVSPDKKYIG LAWASLQSGE FKTKLTTVDK LDDELARLQA AEILLPDSKN
     APQLQTASGV TRLNAWQFAA DAGEKLLTEY FGCQDLRGFG LDGKEHAVAI GAAGALLNYI
     RLTQNLMPQH LDGLSLETDS QYIGMDAATR RNLEITQTLS GKKSPTLMST LDLCATHMGS
     RLLALWLHHP LRNRAHIRAR QEAVAALESQ YKPLQCRLKN IADIERIAAR IAVGNARPRD
     LASLRDSLFE LAQIDLSANG SSLLETLKAV FPENLSTAEQ LRQAILPEPS VWLKDGNVIN
     HGFHPELDEL RRIQNHGDEF LLDLEAKERE RTGLSTLKVE FNRVHGFYIE LSKTQAEQAP
     ADYQRRQTLK NAERFITPEL KAFEDKVLTA QEQALALEKQ LFDGVLKNLQ TALPQLQKAA
     KAAAALDVLS TFSALAKERN FVRPEFADYP AIHIENGRHP VVEQQVRHFT ANHTNLDHKH
     RLMLLTGPNM GGKSTYMRQV ALIVLLAHTG CFVPADAATI GPIDQIFTRI GASDDLASNR
     STFMVEMSET AYILHHATEQ SLVLMDEVGR GTSTFDGLAL AHAVAEHLLQ KNKSFSLFAT
     HYFELTYLPE AHAAAVNMHL SALEQGQDIV FLHQIQPGPA GKSYGIAVAK LAGLPVRALK
     SAQKHLNGLE NQAAANRPQL DIFSTMPSEK GDEPNVGNFV DKAEEKHFEG ILAAALEKLD
     PDSLTPREAL SELYRLKDLC KSVS