Description:
Putative Holliday junction resolvase (EC 3.1.-.-).
Molecular weight: 16584
View which proteins in this organism that is involved with DNA Repair;
classified after biological processes (using data from the GOA project):
DNA repair( GO:0006281 )
Important dates:
16-JUN-2003, integrated into UniProtKB/Swiss-Prot.
01-OCT-2000, sequence version 1.
07-MAR-2006, entry version 26.
Phylogenetic order:
Bacteria Proteobacteria Betaproteobacteria Neisseriales Neisseriaceae Neisseria.
To calculate the pI (Isoelectric point - the pH where a protein has a neutral charge),
go to this page and enter the protein ID (e.g 3MG_ECOLI): http://us.expasy.org/tools/pi_tool.html
Links to references in other databases for protein RUVX_NEIMA:
| Database | Pointer | Add. info#1 | Add. info#2 |
| EMBL | AL162756 | CAB84778.1 | - |
| PIR | B81847 | B81847. | |
| GenomeReviews | AL157959_GR | NMA1551.1 | |
| BioCyc | NMEN65699:NMA1551-MONOMER | -.1 | |
| HAMAP | MF_00651 | - | 1. |
| InterPro | IPR005227 | HJR_YqgF. | |
| InterPro | IPR012337 | RNaseH_fold. | |
| InterPro | IPR006641 | YqgFc. | |
| Pfam | PF03652 | UPF0081 | 1. |
| SMART | SM00732 | YqgFc | 1. |
| TIGRFAMs | TIGR00250 | HJR_YqgF | 1. |
Keywords:
Complete proteome; DNA damage; DNA recombination; DNA repair; Hydrolase; Nuclease.
References:
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Z2491 / Serogroup A / Serotype 4A;
RX MEDLINE=20222556; PubMed=10761919; DOI=10.1038/35006655;
RA Parkhill J., Achtman M., James K.D., Bentley S.D., Churcher C.M.,
RA Klee S.R., Morelli G., Basham D., Brown D., Chillingworth T.,
RA Davies R.M., Davis P., Devlin K., Feltwell T., Hamlin N., Holroyd S.,
RA Jagels K., Leather S., Moule S., Mungall K.L., Quail M.A.,
RA Rajandream M.A., Rutherford K.M., Simmonds M., Skelton J.,
RA Whitehead S., Spratt B.G., Barrell B.G.;
RT "Complete DNA sequence of a serogroup A strain of Neisseria
RT meningitidis Z2491.";
RL Nature 404:502-506(2000).
Feature:
CHAIN 1 151 Putative Holliday junction resolvase.
/FTId=PRO_0000172103.
Comments:
-!- FUNCTION: Could be a nuclease that resolves Holliday junction
intermediates in genetic recombination.
-!- SUBCELLULAR LOCATION: Cytoplasm (Potential).
-!- SIMILARITY: Belongs to the yqgF HJR family.
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Sequence length: 151
MHKIPKGTAL AFDFGEARIG VAQGDAELGL SHPLATVTGG SNDEKFAAIA KLVQEWQPRY
FVVGLPVHTD GTKHEMTHLS RKFGRRLNGR FNLPVYWVDE RLSSVYAESL LSEAQVFGKK
RKSVLDQVAA QAILHGFFEG GPAECFNGRE G