Description:
Putative very-short-patch-repair endonuclease (EC 3.1.-.-).
Molecular weight: 16751
View which proteins in this organism that is involved with DNA Repair;
classified after biological processes (using data from the GOA project):
DNA repair( GO:0006281 ) mismatch repair( GO:0006298 )
Important dates:
01-DEC-2000, integrated into UniProtKB/Swiss-Prot.
01-OCT-2000, sequence version 1.
07-MAR-2006, entry version 27.
Phylogenetic order:
Bacteria Proteobacteria Betaproteobacteria Neisseriales Neisseriaceae Neisseria.
To calculate the pI (Isoelectric point - the pH where a protein has a neutral charge),
go to this page and enter the protein ID (e.g 3MG_ECOLI): http://us.expasy.org/tools/pi_tool.html
Links to references in other databases for protein VSR_NEIMA:
| Database | Pointer | Add. info#1 | Add. info#2 |
| EMBL | AL162753 | CAB83728.1 | - |
| PIR | H81959 | H81959. | |
| HSSP | P09184 | 1VSR | |
| GenomeReviews | AL157959_GR | NMA0429.1 | |
| BioCyc | NMEN65699:NMA0429-MONOMER | -.1 | |
| InterPro | IPR004603 | Vsr. | |
| Pfam | PF03852 | Vsr | 1. |
| PIRSF | PIRSF018267 | VSR_endonuc | 1. |
| ProDom | PD016088 | Vsr | 1. |
Keywords:
Complete proteome; DNA damage; DNA repair; Endonuclease; Hydrolase; Nuclease.
References:
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Z2491 / Serogroup A / Serotype 4A;
RX MEDLINE=20222556; PubMed=10761919; DOI=10.1038/35006655;
RA Parkhill J., Achtman M., James K.D., Bentley S.D., Churcher C.M.,
RA Klee S.R., Morelli G., Basham D., Brown D., Chillingworth T.,
RA Davies R.M., Davis P., Devlin K., Feltwell T., Hamlin N., Holroyd S.,
RA Jagels K., Leather S., Moule S., Mungall K.L., Quail M.A.,
RA Rajandream M.A., Rutherford K.M., Simmonds M., Skelton J.,
RA Whitehead S., Spratt B.G., Barrell B.G.;
RT "Complete DNA sequence of a serogroup A strain of Neisseria
RT meningitidis Z2491.";
RL Nature 404:502-506(2000).
Feature:
CHAIN 1 140 Putative very-short-patch-repair
endonuclease.
/FTId=PRO_0000200294.
Comments:
-!- FUNCTION: May nick specific sequences that contain T:G mispairs
resulting from m5C-deamination (By similarity).
-!- SIMILARITY: Belongs to the vsr family.
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Sequence length: 140
MTDIFTTSKR SFVMLKIHSK ETKPEVLVRK FLFFQGFRYR KNDKRYVGKP DIVLSKYKTV
VFIHGCFWYG HSCNKGHIPK SNTDFWLEKI TKNCERDIKN ETELEKIGFK VIVVWECELK
NKAICRERLN RLVREIKDAV