Description:
Putative Holliday junction resolvase (EC 3.1.-.-).
Molecular weight: 15506
View which proteins in this organism that is involved with DNA Repair;
classified after biological processes (using data from the GOA project):
DNA repair( GO:0006281 )
Important dates:
16-JUN-2003, integrated into UniProtKB/Swiss-Prot.
01-OCT-2000, sequence version 1.
07-MAR-2006, entry version 22.
Phylogenetic order:
Bacteria Proteobacteria Gammaproteobacteria Vibrionales Vibrionaceae Vibrio.
To calculate the pI (Isoelectric point - the pH where a protein has a neutral charge),
go to this page and enter the protein ID (e.g 3MG_ECOLI): http://us.expasy.org/tools/pi_tool.html
Links to references in other databases for protein RUVX_VIBCH:
| Database | Pointer | Add. info#1 | Add. info#2 |
| EMBL | AE004133 | AAF93639.1 | - |
| PIR | G82318 | G82318. | |
| GenomeReviews | AE003852_GR | VC0466.1 | |
| TIGR | VC0466 | -. | |
| LinkHub | Q9KUP9 | -.1 | |
| HAMAP | MF_00651 | - | 1. |
| InterPro | IPR005227 | HJR_YqgF. | |
| InterPro | IPR012337 | RNaseH_fold. | |
| InterPro | IPR006641 | YqgFc. | |
| Pfam | PF03652 | UPF0081 | 1. |
| SMART | SM00732 | YqgFc | 1. |
| TIGRFAMs | TIGR00250 | HJR_YqgF | 1. |
Keywords:
Complete proteome; DNA damage; DNA recombination; DNA repair; Hydrolase; Nuclease.
References:
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=El Tor N16961 / Serotype O1;
RX MEDLINE=20406833; PubMed=10952301; DOI=10.1038/35020000;
RA Heidelberg J.F., Eisen J.A., Nelson W.C., Clayton R.A., Gwinn M.L.,
RA Dodson R.J., Haft D.H., Hickey E.K., Peterson J.D., Umayam L.A.,
RA Gill S.R., Nelson K.E., Read T.D., Tettelin H., Richardson D.L.,
RA Ermolaeva M.D., Vamathevan J.J., Bass S., Qin H., Dragoi I.,
RA Sellers P., McDonald L.A., Utterback T.R., Fleischmann R.D.,
RA Nierman W.C., White O., Salzberg S.L., Smith H.O., Colwell R.R.,
RA Mekalanos J.J., Venter J.C., Fraser C.M.;
RT "DNA sequence of both chromosomes of the cholera pathogen Vibrio
RT cholerae.";
RL Nature 406:477-483(2000).
Feature:
CHAIN 1 140 Putative Holliday junction resolvase.
/FTId=PRO_0000172169.
Comments:
-!- FUNCTION: Could be a nuclease that resolves Holliday junction
intermediates in genetic recombination.
-!- SUBCELLULAR LOCATION: Cytoplasm (Potential).
-!- SIMILARITY: Belongs to the yqgF HJR family.
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Sequence length: 140
MSRTVMAFDY GTKSIGSAIG QEITGTASPL KAFKANDGIP NWDEIEKQIK EWQPNLLIVG
LPTDLHGKDL DTITPRAKKF AQRLHGRFGL PVELHDERLS TTEARAELFA MGGYKALSKG
NVDCQSAVII LESWFESQWG