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Description:
Protein recA (Recombinase A).
Molecular weight: 37433
View which proteins in this organism that is involved with DNA Repair;
classified after biological processes (using data from the GOA project):
DNA repair( GO:0006281 )
Important dates:
30-MAY-2003, integrated into UniProtKB/Swiss-Prot.
30-MAY-2003, sequence version 1.
07-MAR-2006, entry version 23.
Phylogenetic order:
Bacteria Proteobacteria Gammaproteobacteria Vibrionales Vibrionaceae Vibrio.
To calculate the pI (Isoelectric point - the pH where a protein has a neutral charge),
go to this page and enter the protein ID (e.g 3MG_ECOLI): http://us.expasy.org/tools/pi_tool.html
Links to references in other databases for protein RECA_VIBPA:
| Database | Pointer | Add. info#1 | Add. info#2 |
| EMBL | BA000031 | BAC60813.1 | - |
| HSSP | P03017 | 2REB | |
| SMR | Q87LR1 | 2-327.1 | |
| GenomeReviews | BA000031_GR | VP2550.1 | |
| HAMAP | MF_00268 | - | 1. |
| InterPro | IPR003593 | AAA_ATPase. | |
| InterPro | IPR001553 | RecA_bac. | |
| Pfam | PF00154 | RecA | 1. |
| PRINTS | PR00142 | RECA. | |
| ProDom | PD000229 | RecA | 1. |
| SMART | SM00382 | AAA | 1. |
| TIGRFAMs | TIGR02012 | tigrfam_recA | 1. |
| PROSITE | PS00321 | RECA_1 | 1. |
| PROSITE | PS50162 | RECA_2 | 1. |
| PROSITE | PS50163 | RECA_3 | 1. |
Keywords:
ATP-binding; Complete proteome; DNA damage; DNA recombination; DNA repair; DNA-binding; Nucleotide-binding; SOS response.
References:
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=RIMD 2210633 / Serotype O3:K6;
RX MEDLINE=22508454; PubMed=12620739; DOI=10.1016/S0140-6736(03)12659-1;
RA Makino K., Oshima K., Kurokawa K., Yokoyama K., Uda T., Tagomori K.,
RA Iijima Y., Najima M., Nakano M., Yamashita A., Kubota Y., Kimura S.,
RA Yasunaga T., Honda T., Shinagawa H., Hattori M., Iida T.;
RT "Genome sequence of Vibrio parahaemolyticus: a pathogenic mechanism
RT distinct from that of V. cholerae.";
RL Lancet 361:743-749(2003).
Feature:
CHAIN 1 347 Protein recA.
/FTId=PRO_0000122894.
NP_BIND 65 72 ATP (By similarity).
Comments:
-!- FUNCTION: Can catalyze the hydrolysis of ATP in the presence of
single-stranded DNA, the ATP-dependent uptake of single-stranded
DNA by duplex DNA, and the ATP-dependent hybridization of
homologous single-stranded DNAs. It interacts with lexA causing
its activation and leading to its autocatalytic cleavage (By
similarity).
-!- SUBCELLULAR LOCATION: Cytoplasm (By similarity).
-!- SIMILARITY: Belongs to the recA family.
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Sequence length: 347
MDENKQKALA AALGQIEKQF GKGSIMRLGD NRAMDVETIS TGSLSLDIAL GAGGLPMGRI
VEIYGPESSG KTTLTLELIA AAQREGKTCA FIDAEHALDP VYAKKLGVDI DALLVSQPDT
GEQALEICDA LARSGAIDVM VVDSVAALTP KAEIEGEMGD SHMGLQARML SQAMRKLTGN
LKQSNCMCIF INQIRMKIGV MFGNPETTTG GNALKFYASV RLDIRRTGAI KEGDEVVGNE
TRIKVVKNKI AAPFKEANTQ IMYGQGFNRE GELIDLGVKH KLVEKAGAWY SYNGDKIGQG
KANACNYLRE HPEIAKTIDT KLREMLLSPA QPEAPAAGEK PEQEEEF