Description:
Holliday junction ATP-dependent DNA helicase ruvB (EC 3.6.1.-).
Molecular weight: 36760
View which proteins in this organism that is involved with DNA Repair;
classified after biological processes (using data from the GOA project):
DNA repair( GO:0006281 )
Important dates:
25-MAR-2003, integrated into UniProtKB/Swiss-Prot.
01-MAR-2003, sequence version 1.
07-MAR-2006, entry version 25.
Phylogenetic order:
Bacteria Proteobacteria Gammaproteobacteria Alteromonadales Shewanellaceae Shewanella.
To calculate the pI (Isoelectric point - the pH where a protein has a neutral charge),
go to this page and enter the protein ID (e.g 3MG_ECOLI): http://us.expasy.org/tools/pi_tool.html
Links to references in other databases for protein RUVB_SHEON:
| Database | Pointer | Add. info#1 | Add. info#2 |
| EMBL | AE015683 | AAN55463.1 | - |
| HSSP | Q56313 | 1J7K | |
| GenomeReviews | AE014299_GR | SO2429.1 | |
| TIGR | SO2429 | -. | |
| BioCyc | SONE211586:SO2429-MONOMER | -.1 | |
| HAMAP | MF_00016 | - | 1. |
| InterPro | IPR003593 | AAA_ATPase. | |
| InterPro | IPR003959 | AAA_ATPase_centr. | |
| InterPro | IPR000641 | CbxX_CfqX. | |
| InterPro | IPR004605 | RuvB. | |
| InterPro | IPR008823 | RuvB_C. | |
| InterPro | IPR008824 | RuvB_N. | |
| InterPro | IPR011991 | Wing_hlx_DNA_bd. | |
| Pfam | PF00004 | AAA | 1. |
| Pfam | PF05491 | RuvB_C | 1. |
| Pfam | PF05496 | RuvB_N | 1. |
| PRINTS | PR00819 | CBXCFQXSUPER. | |
| SMART | SM00382 | AAA | 1. |
| TIGRFAMs | TIGR00635 | ruvB | 1. |
Keywords:
ATP-binding; Complete proteome; DNA damage; DNA recombination; DNA repair; Helicase; Hydrolase; Nucleotide-binding; SOS response.
References:
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MR-1;
RX MEDLINE=22297686; PubMed=12368813; DOI=10.1038/nbt749;
RA Heidelberg J.F., Paulsen I.T., Nelson K.E., Gaidos E.J., Nelson W.C.,
RA Read T.D., Eisen J.A., Seshadri R., Ward N.L., Methe B.A.,
RA Clayton R.A., Meyer T., Tsapin A., Scott J., Beanan M.J.,
RA Brinkac L.M., Daugherty S.C., DeBoy R.T., Dodson R.J., Durkin A.S.,
RA Haft D.H., Kolonay J.F., Madupu R., Peterson J.D., Umayam L.A.,
RA White O., Wolf A.M., Vamathevan J.J., Weidman J.F., Impraim M.,
RA Lee K., Berry K.J., Lee C., Mueller J., Khouri H.M., Gill J.,
RA Utterback T.R., McDonald L.A., Feldblyum T.V., Smith H.O.,
RA Venter J.C., Nealson K.H., Fraser C.M.;
RT "Genome sequence of the dissimilatory metal ion-reducing bacterium
RT Shewanella oneidensis.";
RL Nat. Biotechnol. 20:1118-1123(2002).
Feature:
CHAIN 1 334 Holliday junction ATP-dependent DNA
helicase ruvB.
/FTId=PRO_0000165592.
NP_BIND 62 69 ATP (Potential).
Comments:
-!- FUNCTION: The ruvA-ruvB complex in the presence of ATP renatures
cruciform structure in supercoiled DNA with palindromic sequence,
indicating that it may promote strand exchange reactions in
homologous recombination. RuvAB is an helicase that mediates the
Holliday junction migration by localized denaturation and
reannealing (By similarity).
-!- SUBUNIT: Forms a complex with ruvA (By similarity).
-!- SIMILARITY: Belongs to the ruvB family.
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Sequence length: 334
MIEADRLIQP QLQGQDDVID RAMRPKLLDE YTGQDDTRAQ LKVFIQAAKN REEALDHMLI
YGPPGLGKTT LAMIVANEMG VNIKSTSGPV LEKAGDLAAL LTNLEAGDVL FIDEIHRLSP
VVEEILYPAM EDYQLDIMIG EGPAARSIKL DLPPFTLVGA TTRAGALTSP LRARFGIPLR
LEFYNVKDLS TIVTRSAQVM GLAIDSEGAT EIAKRSRGTP RIANRLLRRV RDYAEVQHDG
AVTQNVAELA LNLLDVDGEG FDYMDRKLLL AIIDKFMGGP VGLDNLAAAI GEERETIEDV
LEPFLIQQGF IQRTPRGRIA TARAYVHFGM IKPE