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Description:
DNA mismatch repair protein mutS.
Molecular weight: 10211
View which proteins in this organism that is involved with DNA Repair;
classified after biological processes (using data from the GOA project):
DNA repair( GO:0006281 ) mismatch repair( GO:0006298 )
Important dates:
01-MAR-2004, integrated into UniProtKB/Swiss-Prot.
01-JUN-2002, sequence version 1.
07-MAR-2006, entry version 24.
Phylogenetic order:
Bacteria Fusobacteria Fusobacterales Fusobacteriaceae Fusobacterium.
To calculate the pI (Isoelectric point - the pH where a protein has a neutral charge),
go to this page and enter the protein ID (e.g 3MG_ECOLI): http://us.expasy.org/tools/pi_tool.html
Links to references in other databases for protein MUTS_FUSNN:
| Database | Pointer | Add. info#1 | Add. info#2 |
| EMBL | AE009951 | AAL94889.1 | - |
| HSSP | P23909 | 1OH6 | |
| GenomeReviews | AE009951_GR | FN0693.1 | |
| HAMAP | MF_00096 | - | 1. |
| InterPro | IPR005748 | MutS1. | |
| InterPro | IPR000432 | MutS_C. | |
| InterPro | IPR007860 | MutS_II. | |
| InterPro | IPR007696 | MutS_III. | |
| InterPro | IPR007861 | MutS_IV. | |
| InterPro | IPR007695 | MutS_N. | |
| PANTHER | PTHR11361:SF23 | MutS.1 | 1. |
| Pfam | PF01624 | MutS_I | 1. |
| Pfam | PF05188 | MutS_II | 1. |
| Pfam | PF05192 | MutS_III | 1. |
| Pfam | PF05190 | MutS_IV | 1. |
| Pfam | PF00488 | MutS_V | 1. |
| ProDom | PD001263 | MutS_C | 1. |
| SMART | SM00534 | MUTSac | 1. |
| SMART | SM00533 | MUTSd | 1. |
| TIGRFAMs | TIGR01070 | mutS1 | 1. |
| PROSITE | PS00486 | DNA_MISMATCH_REPAIR_2 | 1. |
Keywords:
ATP-binding; Complete proteome; DNA damage; DNA repair; DNA-binding; Nucleotide-binding.
References:
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 25586;
RX MEDLINE=21886394; PubMed=11889109;
RX DOI=10.1128/JB.184.7.2005-2018.2002;
RA Kapatral V., Anderson I., Ivanova N., Reznik G., Los T., Lykidis A.,
RA Bhattacharyya A., Bartman A., Gardner W., Grechkin G., Zhu L.,
RA Vasieva O., Chu L., Kogan Y., Chaga O., Goltsman E., Bernal A.,
RA Larsen N., D'Souza M., Walunas T., Pusch G., Haselkorn R.,
RA Fonstein M., Kyrpides N.C., Overbeek R.;
RT "Genome sequence and analysis of the oral bacterium Fusobacterium
RT nucleatum strain ATCC 25586.";
RL J. Bacteriol. 184:2005-2018(2002).
Feature:
CHAIN 1 896 DNA mismatch repair protein mutS.
/FTId=PRO_0000115098.
NP_BIND 638 645 ATP (Potential).
Comments:
-!- FUNCTION: This protein is involved in the repair of mismatches in
DNA. It is possible that it carries out the mismatch recognition
step. This protein has a weak ATPase activity (By similarity).
-!- SIMILARITY: Belongs to the DNA mismatch repair mutS family.
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Sequence length: 896
MLKYISYSEK RKIKLRGIKM SADTPLMQQY KKIKEEYQNE ILMFRLGDFY EMFFEDAKIA
SKELGLTLTK RNREKGQDVP LAGVPYHSVA SYIAKLVEKG YSVAICDQVE DPKSATGIVK
REVTRVITPG TIIDVDFLDK NNNNYIACIK INTTENIVAI AYTDITTGEF SVFEIKGKNF
FEKALAEMNK IQASEILLDE KTYSEYIEIL KEKISFLGVK FTEVPNVRKA ESYLTSYFDI
MSIEVFSLKS KDLAISTSAN LLHYIDELQK GNELPFSKIE YKNIDNIMEL NISTQNNLNL
VPKRNEEAKG TLLGVLDNCV TSVGSRELKK IIKNPFLDIE KIKQRQFYVD YFYNDVLLRE
NIREYLKDIY DVERIAGKII YGTENGKDLL SLKESIRKSL ETYKVLKEHQ EIKDILDIDV
KILLDIYNKI ELIINIEAPF SVREGGIIKD GYNSELDKLR KISKLGKDFI LEIEQRERER
TGIKGLKIKY NKVFGYFIEV TKANEHLVPE DYIRKQTLVN SERYIVPDLK EYEEKVITAK
SKIEALEYEL FKQLTSEIKG HIDSLYKLAN RIANLDIVSN FAHIATKNSY VKPEIGDGDI
LEIKGGRHPI VESLIPSGTY VKNDIILDDK NNLIILTGPN MSGKSTYMKQ VALNIIMAHI
GSYVAADCAK IPIVDKIFTR VGASDDLLTG QSTFMLEMTE VASILNNATN KSFIVLDEIG
RGTSTYDGIS IATAITEYIH NNIGAKTIFA THYHELTELE KELERAINFR VEVKEDGKNV
VFLREIVKGG ADKSYGIEVA RLSGVPKEVL NRSNKILKKL ETRKNLIENK IKAEQMILFG
NGFEEENEEE ETEILSENES KVLELLKNMD LNSLSPLESL LKLNELKKIL IGGTDE