Description:
Putative Holliday junction resolvase (EC 3.1.-.-).
Molecular weight: 15693
View which proteins in this organism that is involved with DNA Repair;
classified after biological processes (using data from the GOA project):
DNA repair( GO:0006281 )
Important dates:
16-JUN-2003, integrated into UniProtKB/Swiss-Prot.
01-JUN-2002, sequence version 1.
07-MAR-2006, entry version 21.
Phylogenetic order:
Bacteria Fusobacteria Fusobacterales Fusobacteriaceae Fusobacterium.
To calculate the pI (Isoelectric point - the pH where a protein has a neutral charge),
go to this page and enter the protein ID (e.g 3MG_ECOLI): http://us.expasy.org/tools/pi_tool.html
Links to references in other databases for protein RUVX_FUSNN:
| Database | Pointer | Add. info#1 | Add. info#2 |
| EMBL | AE009951 | AAL94894.1 | - |
| GenomeReviews | AE009951_GR | FN0698.1 | |
| BioCyc | FNUC190304:FN0698-MONOMER | -.1 | |
| HAMAP | MF_00651 | - | 1. |
| InterPro | IPR005227 | HJR_YqgF. | |
| InterPro | IPR012337 | RNaseH_fold. | |
| InterPro | IPR006641 | YqgFc. | |
| Pfam | PF03652 | UPF0081 | 1. |
| SMART | SM00732 | YqgFc | 1. |
| TIGRFAMs | TIGR00250 | HJR_YqgF | 1. |
Keywords:
Complete proteome; DNA damage; DNA recombination; DNA repair; Hydrolase; Nuclease.
References:
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 25586;
RX MEDLINE=21886394; PubMed=11889109;
RX DOI=10.1128/JB.184.7.2005-2018.2002;
RA Kapatral V., Anderson I., Ivanova N., Reznik G., Los T., Lykidis A.,
RA Bhattacharyya A., Bartman A., Gardner W., Grechkin G., Zhu L.,
RA Vasieva O., Chu L., Kogan Y., Chaga O., Goltsman E., Bernal A.,
RA Larsen N., D'Souza M., Walunas T., Pusch G., Haselkorn R.,
RA Fonstein M., Kyrpides N.C., Overbeek R.;
RT "Genome sequence and analysis of the oral bacterium Fusobacterium
RT nucleatum strain ATCC 25586.";
RL J. Bacteriol. 184:2005-2018(2002).
Feature:
CHAIN 1 138 Putative Holliday junction resolvase.
/FTId=PRO_0000172066.
Comments:
-!- FUNCTION: Could be a nuclease that resolves Holliday junction
intermediates in genetic recombination.
-!- SUBCELLULAR LOCATION: Cytoplasm (Potential).
-!- SIMILARITY: Belongs to the yqgF HJR family.
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Sequence length: 138
MKRYIALDIG DVRIGVARSD IMGIIASPLE TINRKKVKSV KRIAEICKEN DTNLVVVGIP
KSLDGEEKRQ AEKVREYIEK LKKEIENLEI IEVDERFSTV IADNILKELN KNGAIEKRKV
VDKVAASIIL QTYLDMKK