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Description:
Protein recA (Recombinase A).
Molecular weight: 37250
View which proteins in this organism that is involved with DNA Repair;
classified after biological processes (using data from the GOA project):
DNA repair( GO:0006281 )
Important dates:
16-APR-2002, integrated into UniProtKB/Swiss-Prot.
16-APR-2002, sequence version 2.
07-MAR-2006, entry version 25.
Phylogenetic order:
Bacteria Proteobacteria Alphaproteobacteria Rickettsiales Rickettsiaceae Rickettsieae Rickettsia spotted fever group.
To calculate the pI (Isoelectric point - the pH where a protein has a neutral charge),
go to this page and enter the protein ID (e.g 3MG_ECOLI): http://us.expasy.org/tools/pi_tool.html
Links to references in other databases for protein RECA_RICCN:
| Database | Pointer | Add. info#1 | Add. info#2 |
| EMBL | AE008666 | AAL03720.1 | ALT_INIT |
| HSSP | P03017 | 2REB | |
| GenomeReviews | AE006914_GR | RC1182.1 | |
| BioCyc | RCON781:RC1182-MONOMER | -.1 | |
| HAMAP | MF_00268 | - | 1. |
| InterPro | IPR003593 | AAA_ATPase. | |
| InterPro | IPR001553 | RecA_bac. | |
| Pfam | PF00154 | RecA | 1. |
| PRINTS | PR00142 | RECA. | |
| ProDom | PD000229 | RecA | 1. |
| SMART | SM00382 | AAA | 1. |
| TIGRFAMs | TIGR02012 | tigrfam_recA | 1. |
| PROSITE | PS00321 | RECA_1 | 1. |
| PROSITE | PS50162 | RECA_2 | 1. |
| PROSITE | PS50163 | RECA_3 | 1. |
Keywords:
ATP-binding; Complete proteome; DNA damage; DNA recombination; DNA repair; DNA-binding; Nucleotide-binding; SOS response.
References:
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Malish 7;
RX MEDLINE=21442074; PubMed=11557893; DOI=10.1126/science.1061471;
RA Ogata H., Audic S., Renesto-Audiffren P., Fournier P.-E., Barbe V.,
RA Samson D., Roux V., Cossart P., Weissenbach J., Claverie J.-M.,
RA Raoult D.;
RT "Mechanisms of evolution in Rickettsia conorii and R. prowazekii.";
RL Science 293:2093-2098(2001).
Feature:
CHAIN 1 343 Protein recA.
/FTId=PRO_0000122821.
NP_BIND 66 73 ATP (By similarity).
Comments:
-!- FUNCTION: Can catalyze the hydrolysis of ATP in the presence of
single-stranded DNA, the ATP-dependent uptake of single-stranded
DNA by duplex DNA, and the ATP-dependent hybridization of
homologous single-stranded DNAs. It interacts with lexA causing
its activation and leading to its autocatalytic cleavage (By
similarity).
-!- SUBCELLULAR LOCATION: Cytoplasm (By similarity).
-!- SIMILARITY: Belongs to the recA family.
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Sequence length: 343
MSNTDKERAI AAALAQIEKS YGKGSVMKLG QRPHVDIEAV STGSLGLDIA LGIGGVPKGR
IIEIFGPESS GKTTLTLHLI AEAQKKGGTC AFIDAEHALD PAYAKKLGVN IDELIISQPD
TGEQALEIAD TLIRSSGIDM IIIDSVAALV PKSEIEGEMG DAQMASQARL MSQALRKLTA
SINRTNCITV FINQIRMKIG VMFGSPETTT GGNALKFYAS VRIDIRRIGS IKDKEEVIGS
QTKVKVVKNK VSPPFKTADF DIMYGSGISK EGEIIDLGVK LDIVEKSGSW FSYKNVRIGQ
GRENVKQYLK EHPQISNEIE KIIREKSSKI TNINLDQTEE END