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Description:
DNA replication and repair protein recF.
Molecular weight: 41527
View which proteins in this organism that is involved with DNA Repair;
classified after biological processes (using data from the GOA project):
DNA repair( GO:0006281 )
Important dates:
15-MAY-2002, integrated into UniProtKB/Swiss-Prot.
01-DEC-2001, sequence version 1.
07-MAR-2006, entry version 23.
Phylogenetic order:
Bacteria Proteobacteria Alphaproteobacteria Rickettsiales Rickettsiaceae Rickettsieae Rickettsia spotted fever group.
To calculate the pI (Isoelectric point - the pH where a protein has a neutral charge),
go to this page and enter the protein ID (e.g 3MG_ECOLI): http://us.expasy.org/tools/pi_tool.html
Links to references in other databases for protein RECF_RICCN:
| Database | Pointer | Add. info#1 | Add. info#2 |
| EMBL | AE008571 | AAL02570.1 | - |
| PIR | H97703 | H97703. | |
| GenomeReviews | AE006914_GR | RC0032.1 | |
| BioCyc | RCON781:RC0032-MONOMER | -.1 | |
| HAMAP | MF_00365 | - | 1. |
| InterPro | IPR003439 | ABC_transp_like. | |
| InterPro | IPR001238 | RecF. | |
| InterPro | IPR003395 | SMC_N. | |
| Pfam | PF02463 | SMC_N | 1. |
| TIGRFAMs | TIGR00611 | recf | 1. |
| PROSITE | PS00617 | RECF_1 | 1. |
| PROSITE | PS00618 | RECF_2 | 1. |
Keywords:
ATP-binding; Complete proteome; DNA damage; DNA repair; DNA replication; DNA-binding; Nucleotide-binding; SOS response.
References:
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Malish 7;
RX MEDLINE=21442074; PubMed=11557893; DOI=10.1126/science.1061471;
RA Ogata H., Audic S., Renesto-Audiffren P., Fournier P.-E., Barbe V.,
RA Samson D., Roux V., Cossart P., Weissenbach J., Claverie J.-M.,
RA Raoult D.;
RT "Mechanisms of evolution in Rickettsia conorii and R. prowazekii.";
RL Science 293:2093-2098(2001).
Feature:
CHAIN 1 360 DNA replication and repair protein recF.
/FTId=PRO_0000196449.
NP_BIND 33 40 ATP (Potential).
Comments:
-!- FUNCTION: The recF protein is involved in DNA metabolism; it is
required for DNA replication and normal SOS inducibility. RecF
binds preferentially to single-stranded, linear DNA. It also seems
to bind ATP (By similarity).
-!- SUBCELLULAR LOCATION: Cytoplasm (By similarity).
-!- SIMILARITY: Belongs to the recF family.
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Sequence length: 360
MKNIFLHSLN LENYRNFKNL ELKTDNTPII LIGENGSGKT NILEAISLFY PGRGLRSAKL
ANVCKTSEDH CLVKALLQSK LGLAEFTTQF KRSSNRRITE YNESKIANNE LSKFTSMVWL
TPHMEGIFTS GSSDRRKFLD RIVYNFDPKH AELVSKYEYY MHERNKILVE DRRDDNWLKI
IEEKMADISN HIANNRLKTL EFMQQAIDDL ENEFPKADLS IDGIVEQKIL NGKKNIVSFI
TAELYQTRSK DKLLGRTSFG VHKSDFLVKH QKKNILAKFC STGEQKAILI AIILAEMNYA
IKLTKIAPIL LLDEVFVHLD DKRRQYLIEF LTGLNMQLWV TTTNLEGIDN FATKAQLIKL