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Description:
Putative Holliday junction resolvase (EC 3.1.-.-).
Molecular weight: 17172
View which proteins in this organism that is involved with DNA Repair;
classified after biological processes (using data from the GOA project):
DNA repair( GO:0006281 )
Important dates:
16-JUN-2003, integrated into UniProtKB/Swiss-Prot.
01-DEC-2001, sequence version 1.
07-MAR-2006, entry version 19.
Phylogenetic order:
Bacteria Proteobacteria Alphaproteobacteria Rickettsiales Rickettsiaceae Rickettsieae Rickettsia spotted fever group.
To calculate the pI (Isoelectric point - the pH where a protein has a neutral charge),
go to this page and enter the protein ID (e.g 3MG_ECOLI): http://us.expasy.org/tools/pi_tool.html
Links to references in other databases for protein RUVX_RICCN:
| Database | Pointer | Add. info#1 | Add. info#2 |
| EMBL | AE008609 | AAL02993.1 | - |
| PIR | G97756 | G97756. | |
| GenomeReviews | AE006914_GR | RC0455.1 | |
| BioCyc | RCON781:RC0455-MONOMER | -.1 | |
| HAMAP | MF_00651 | - | 1. |
| InterPro | IPR005227 | HJR_YqgF. | |
| InterPro | IPR012337 | RNaseH_fold. | |
| InterPro | IPR006641 | YqgFc. | |
| Pfam | PF03652 | UPF0081 | 1. |
| SMART | SM00732 | YqgFc | 1. |
| TIGRFAMs | TIGR00250 | HJR_YqgF | 1. |
Keywords:
Complete proteome; DNA damage; DNA recombination; DNA repair; Hydrolase; Nuclease.
References:
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Malish 7;
RX MEDLINE=21442074; PubMed=11557893; DOI=10.1126/science.1061471;
RA Ogata H., Audic S., Renesto-Audiffren P., Fournier P.-E., Barbe V.,
RA Samson D., Roux V., Cossart P., Weissenbach J., Claverie J.-M.,
RA Raoult D.;
RT "Mechanisms of evolution in Rickettsia conorii and R. prowazekii.";
RL Science 293:2093-2098(2001).
Feature:
CHAIN 1 154 Putative Holliday junction resolvase.
/FTId=PRO_0000172128.
Comments:
-!- FUNCTION: Could be a nuclease that resolves Holliday junction
intermediates in genetic recombination.
-!- SUBCELLULAR LOCATION: Cytoplasm (Potential).
-!- SIMILARITY: Belongs to the yqgF HJR family.
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Sequence length: 154
MIIKNLQEFY RLLIPNVPLI AIDYGNKKLG IALSNQERSI AMPLNTITEI NKKIVITSLL
NIIEKYKVCG VIIGLPIDMS GAVTEQTNIV MKFAEELAKS INLPIYLQDE RLTTKAANNL
LKSFGVKRKD RNNNDDAVAA SMILETVLDS IKNI