Description:
Putative Holliday junction resolvase (EC 3.1.-.-).
Molecular weight: 17435
View which proteins in this organism that is involved with DNA Repair;
classified after biological processes (using data from the GOA project):
DNA repair( GO:0006281 )
Important dates:
30-MAY-2000, integrated into UniProtKB/Swiss-Prot.
01-MAY-1999, sequence version 1.
07-MAR-2006, entry version 28.
Phylogenetic order:
Bacteria Proteobacteria Alphaproteobacteria Rickettsiales Rickettsiaceae Rickettsieae Rickettsia typhus group.
To calculate the pI (Isoelectric point - the pH where a protein has a neutral charge),
go to this page and enter the protein ID (e.g 3MG_ECOLI): http://us.expasy.org/tools/pi_tool.html
Links to references in other databases for protein RUVX_RICPR:
| Database | Pointer | Add. info#1 | Add. info#2 |
| EMBL | AJ235271 | CAA14790.1 | - |
| PIR | D71689 | D71689. | |
| GenomeReviews | AJ235269_GR | RP330.1 | |
| BioCyc | RPRO782:RP330-MONOMER | -.1 | |
| HAMAP | MF_00651 | - | 1. |
| InterPro | IPR005227 | HJR_YqgF. | |
| InterPro | IPR012337 | RNaseH_fold. | |
| InterPro | IPR006641 | YqgFc. | |
| Pfam | PF03652 | UPF0081 | 1. |
| SMART | SM00732 | YqgFc | 1. |
| TIGRFAMs | TIGR00250 | HJR_YqgF | 1. |
Keywords:
Complete proteome; DNA damage; DNA recombination; DNA repair; Hydrolase; Nuclease.
References:
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Madrid E;
RX MEDLINE=99039499; PubMed=9823893; DOI=10.1038/24094;
RA Andersson S.G.E., Zomorodipour A., Andersson J.O.,
RA Sicheritz-Ponten T., Alsmark U.C.M., Podowski R.M., Naeslund A.K.,
RA Eriksson A.-S., Winkler H.H., Kurland C.G.;
RT "The genome sequence of Rickettsia prowazekii and the origin of
RT mitochondria.";
RL Nature 396:133-140(1998).
Feature:
CHAIN 1 156 Putative Holliday junction resolvase.
/FTId=PRO_0000172129.
Comments:
-!- FUNCTION: Could be a nuclease that resolves Holliday junction
intermediates in genetic recombination.
-!- SUBCELLULAR LOCATION: Cytoplasm (Potential).
-!- SIMILARITY: Belongs to the yqgF HJR family.
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Sequence length: 156
MIIKNLQEFY RLLIPNKPLI AIDYGSKKIG VALSDQELSI AMPFNTITAV NKKVVITSLL
NIIKKYKVCG IVIGLPIDMS GGVTQQTNIV MKFAEKLKQS LGLPIYLQDE RLTTKSANNF
LKSFGIKRKD RNHNDDAVAA SMILEIVLNA IKRFNL