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Description:
DNA replication and repair protein recF.
Molecular weight: 40383
View which proteins in this organism that is involved with DNA Repair;
classified after biological processes (using data from the GOA project):
DNA repair( GO:0006281 )
Important dates:
21-JUL-1986, integrated into UniProtKB/Swiss-Prot.
07-JUN-2005, sequence version 1.
07-MAR-2006, entry version 7.
Phylogenetic order:
Bacteria Proteobacteria Gammaproteobacteria Enterobacteriales Enterobacteriaceae Escherichia.
To calculate the pI (Isoelectric point - the pH where a protein has a neutral charge),
go to this page and enter the protein ID (e.g 3MG_ECOLI): http://us.expasy.org/tools/pi_tool.html
Links to references in other databases for protein RECF_ECO57:
| Database | Pointer | Add. info#1 | Add. info#2 |
| EMBL | AE005174 | AAG58897.1 | - |
| EMBL | BA000007 | BAB38058.1 | - |
| PIR | C91208 | C91208. | |
| PIR | E86054 | E86054. | |
| HSSP | P58301 | 1F2T | |
| GenomeReviews | BA000007_GR | ECs4635.1 | |
| GenomeReviews | AE005174_GR | z5191.1 | |
| HAMAP | MF_00365 | - | 1. |
| InterPro | IPR001238 | RecF. | |
| InterPro | IPR002017 | Spectrin. | |
| Pfam | PF02463 | SMC_N | 1. |
| TIGRFAMs | TIGR00611 | recf | 1. |
| PROSITE | PS00617 | RECF_1 | 1. |
| PROSITE | PS00618 | RECF_2 | 1. |
Keywords:
ATP-binding; Complete proteome; DNA damage; DNA repair; DNA replication; DNA-binding; Nucleotide-binding; SOS response.
References:
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=O157:H7 / EDL933 / ATCC 700927 / EHEC;
RX MEDLINE=21074935; PubMed=11206551; DOI=10.1038/35054089;
RA Perna N.T., Plunkett G. III, Burland V., Mau B., Glasner J.D.,
RA Rose D.J., Mayhew G.F., Evans P.S., Gregor J., Kirkpatrick H.A.,
RA Posfai G., Hackett J., Klink S., Boutin A., Shao Y., Miller L.,
RA Grotbeck E.J., Davis N.W., Lim A., Dimalanta E.T., Potamousis K.,
RA Apodaca J., Anantharaman T.S., Lin J., Yen G., Schwartz D.C.,
RA Welch R.A., Blattner F.R.;
RT "Genome sequence of enterohaemorrhagic Escherichia coli O157:H7.";
RL Nature 409:529-533(2001).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=O157:H7 / Sakai / RIMD 0509952 / EHEC;
RX MEDLINE=21156231; PubMed=11258796; DOI=10.1093/dnares/8.1.11;
RA Hayashi T., Makino K., Ohnishi M., Kurokawa K., Ishii K., Yokoyama K.,
RA Han C.-G., Ohtsubo E., Nakayama K., Murata T., Tanaka M., Tobe T.,
RA Iida T., Takami H., Honda T., Sasakawa C., Ogasawara N., Yasunaga T.,
RA Kuhara S., Shiba T., Hattori M., Shinagawa H.;
RT "Complete genome sequence of enterohemorrhagic Escherichia coli
RT O157:H7 and genomic comparison with a laboratory strain K-12.";
RL DNA Res. 8:11-22(2001).
Feature:
INIT_MET 0 0 By similarity.
CHAIN 1 356 DNA replication and repair protein recF.
/FTId=PRO_0000196415.
NP_BIND 29 36 ATP (Potential).
Comments:
-!- FUNCTION: The recF protein is involved in DNA metabolism; it is
required for DNA replication and normal SOS inducibility. RecF
binds preferentially to single-stranded, linear DNA. It also seems
to bind ATP (By similarity).
-!- SUBCELLULAR LOCATION: Cytoplasm (By similarity).
-!- SIMILARITY: Belongs to the recF family.
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Sequence length: 356
SLTRLLIRDF RNIETADLAL SPGFNFLVGA NGSGKTSVLE AIYTLGHGRA FRSLQIGRVI
RHEQEAFVLH GRLQGEERET AIGLTKDKQG DSKVRIDGTD GHKVAELAHL MPMQLITPEG
FTLLNGGPKY RRAFLDWGCF HNEPGFFTAW SNLKRLLKQR NAALRQVTRY EQLRPWDKEL
IPLAEQISTW RAEYSAGIAA DMADTCKQFL PEFSLTFSFQ RGWEKETEYA EVLERNFERD
RQLTYTAHGP HKADLRIRAD GAPVEDTLSR GQLKLLMCAL RLAQGEFLTR ESGRRCLYLI
DDFASELDDE RRGLLASRLK ATQSQVFVSA ISAEHVIDMS DENSKMFTVE KGKITD