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Description:
Probable ATP-dependent Clp protease ATP-binding subunit.
Molecular weight: 94981
View which proteins in this organism that is involved with DNA Repair;
classified after biological processes (using data from the GOA project):
nucleotide-excision repair (and GO:0045001, a synonym)( GO:0006289 )
Important dates:
01-JUN-2001, integrated into UniProtKB/Swiss-Prot.
01-JUN-2001, sequence version 2.
07-MAR-2006, entry version 40.
Phylogenetic order:
Bacteria Chlamydiae Chlamydiales Chlamydiaceae Chlamydophila.
To calculate the pI (Isoelectric point - the pH where a protein has a neutral charge),
go to this page and enter the protein ID (e.g 3MG_ECOLI): http://us.expasy.org/tools/pi_tool.html
Links to references in other databases for protein CLPC_CHLPN:
| Database | Pointer | Add. info#1 | Add. info#2 |
| EMBL | AE001626 | AAD18581.1 | - |
| EMBL | AE002194 | AAF38172.1 | - |
| EMBL | BA000008 | BAA98645.1 | - |
| EMBL | AE017158 | AAP98384.1 | - |
| PIR | C86545 | C86545. | |
| PIR | G72079 | G72079. | |
| PIR | G81590 | G81590. | |
| HSSP | P03815 | 1JBK | |
| PHCI-2DPAGE | Q9Z8A6 | -. | |
| GenomeReviews | BA000008_GR | clpC.1 | |
| GenomeReviews | AE002161_GR | CP0316.1 | |
| GenomeReviews | AE009440_GR | CpB0454.1 | |
| GenomeReviews | AE001363_GR | CPn0437.1 | |
| TIGR | CP0316 | -. | |
| BioCyc | CPNE115711:CP0316-MONOMER | -.1 | |
| BioCyc | CPNE115713:CPN0437-MONOMER | -.1 | |
| BioCyc | CPNE182082:CPB0454-MONOMER | -.1 | |
| InterPro | IPR013093 | AAA_2. | |
| InterPro | IPR003593 | AAA_ATPase. | |
| InterPro | IPR003959 | AAA_ATPase_centr. | |
| InterPro | IPR001270 | Chaprnin_clpA/B. | |
| InterPro | IPR004176 | Clp_N. | |
| InterPro | IPR001943 | UvrB/C. | |
| Pfam | PF00004 | AAA | 1. |
| Pfam | PF07724 | AAA_2 | 1. |
| Pfam | PF02861 | Clp_N | 2. |
| Pfam | PF02151 | UVR | 1. |
| PRINTS | PR00300 | CLPPROTEASEA. | |
| SMART | SM00382 | AAA | 2. |
| PROSITE | PS00870 | CLPAB_1 | 1. |
| PROSITE | PS50151 | UVR | 1. |
Keywords:
ATP-binding; Chaperone; Complete proteome; Nucleotide-binding; Repeat.
References:
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CWL029;
RX MEDLINE=99206606; PubMed=10192388; DOI=10.1038/7716;
RA Kalman S., Mitchell W.P., Marathe R., Lammel C.J., Fan J., Hyman R.W.,
RA Olinger L., Grimwood J., Davis R.W., Stephens R.S.;
RT "Comparative genomes of Chlamydia pneumoniae and C. trachomatis.";
RL Nat. Genet. 21:385-389(1999).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=AR39;
RX MEDLINE=20150255; PubMed=10684935; DOI=10.1093/nar/28.6.1397;
RA Read T.D., Brunham R.C., Shen C., Gill S.R., Heidelberg J.F.,
RA White O., Hickey E.K., Peterson J.D., Utterback T.R., Berry K.J.,
RA Bass S., Linher K.D., Weidman J.F., Khouri H.M., Craven B., Bowman C.,
RA Dodson R.J., Gwinn M.L., Nelson W.C., DeBoy R.T., Kolonay J.F.,
RA McClarty G., Salzberg S.L., Eisen J.A., Fraser C.M.;
RT "Genome sequences of Chlamydia trachomatis MoPn and Chlamydia
RT pneumoniae AR39.";
RL Nucleic Acids Res. 28:1397-1406(2000).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=J138;
RX MEDLINE=20330349; PubMed=10871362; DOI=10.1093/nar/28.12.2311;
RA Shirai M., Hirakawa H., Kimoto M., Tabuchi M., Kishi F., Ouchi K.,
RA Shiba T., Ishii K., Hattori M., Kuhara S., Nakazawa T.;
RT "Comparison of whole genome sequences of Chlamydia pneumoniae J138
RT from Japan and CWL029 from USA.";
RL Nucleic Acids Res. 28:2311-2314(2000).
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=TW-183;
RA Geng M.M., Schuhmacher A., Muehldorfer I., Bensch K.W., Schaefer K.P.,
RA Schneider S., Pohl T., Essig A., Marre R., Melchers K.;
RT "The genome sequence of Chlamydia pneumoniae TW183 and comparison with
RT other Chlamydia strains based on whole genome sequence analysis.";
RL Submitted (MAY-2002) to the EMBL/GenBank/DDBJ databases.
Feature:
CHAIN 1 845 Probable ATP-dependent Clp protease ATP-
binding subunit.
/FTId=PRO_0000191231.
DOMAIN 441 476 UVR.
NP_BIND 232 239 ATP (Potential).
NP_BIND 569 576 ATP (Potential).
CONFLICT 4 4 K -> T (in Ref. 3).
CONFLICT 141 141 K -> R (in Ref. 1).
Comments:
-!- SIMILARITY: Belongs to the clpA/clpB family. ClpC subfamily.
-!- SIMILARITY: Contains 1 UVR domain.
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Sequence length: 845
MFEKFTNRAK QVIKLAKKEA QRLNHNYLGT EHILLGLLKL GQGVAVNVLR NLGIDFDTAR
QEVERLIGYG PEIQVYGDPA LTGRVKKSFE SANEEASLLE HNYVGTEHLL LGILHQSDSV
ALQVLENLHI DPREVRKEIL KELETFNLQL PPSSSSSSSS SRSNPSSSKS PLGHSLGSDK
NEKLSALKAY GYDLTEMVRE SKLDPVIGRS SEVERLILIL CRRRKNNPVL IGEAGVGKTA
IVEGLAQKII LNEVPDALRK KRLITLDLAL MIAGTKYRGQ FEERIKAVMD EVRKHGNILL
FIDELHTIVG AGAAEGAIDA SNILKPALAR GEIQCIGATT IDEYRKHIEK DAALERRFQK
IVVHPPSVDE TIEILRGLKK KYEEHHNVFI TEEALKAAAT LSDQYVHGRF LPDKAIDLLD
EAGARVRVNT MGQPTDLMKL EAEIENTKLA KEQAIGTQEY EKAAGLRDEE KKLRERLQSM
KQEWENHKEE HQVPVDEEAV AQVVSLQTGI PSARLTEAES EKLLKLEDTL RRKVIGQNDA
VTSICRAIRR SRTGIKDPNR PTGSFLFLGP TGVGKSLLAQ QIAIEMFGGE DALIQVDMSE
YMEKFAATKM MGSPPGYVGH EEGGHLTEQV RRRPYCVVLF DEIEKAHPDI MDLMLQILEQ
GRLTDSFGRK VDFRHAIIIM TSNLGADLIR KSGEIGFGLK SHMDYKVIQE KIEHAMKKHL
KPEFINRLDE SVIFRPLEKE SLSEIIHLEI NKLDSRLKNY QMALNIPDSV ISFLVTKGHS
PEMGARPLRR VIEQYLEDPL AELLLKESCR QEARKLRATL VENRVAFERE EEEQEAALPS
PHLES