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Description:
Protein recA (Recombinase A).
Molecular weight: 38228
View which proteins in this organism that is involved with DNA Repair;
classified after biological processes (using data from the GOA project):
DNA repair( GO:0006281 )
Important dates:
30-MAY-2000, integrated into UniProtKB/Swiss-Prot.
01-MAY-1999, sequence version 1.
07-MAR-2006, entry version 43.
Phylogenetic order:
Bacteria Chlamydiae Chlamydiales Chlamydiaceae Chlamydophila.
To calculate the pI (Isoelectric point - the pH where a protein has a neutral charge),
go to this page and enter the protein ID (e.g 3MG_ECOLI): http://us.expasy.org/tools/pi_tool.html
Links to references in other databases for protein RECA_CHLPN:
| Database | Pointer | Add. info#1 | Add. info#2 |
| EMBL | AE001658 | AAD18900.1 | - |
| EMBL | AE002267 | AAF38877.1 | - |
| EMBL | BA000008 | BAA98970.1 | - |
| EMBL | AE017159 | AAP98719.1 | - |
| PIR | E72037 | E72037. | |
| PIR | H86585 | H86585. | |
| HSSP | P26345 | 1MO3 | |
| PHCI-2DPAGE | Q9Z7E4 | -. | |
| GenomeReviews | AE002161_GR | CP1110.1 | |
| GenomeReviews | AE009440_GR | CpB0790.1 | |
| GenomeReviews | AE001363_GR | CPn0762.1 | |
| GenomeReviews | BA000008_GR | recA.1 | |
| TIGR | CP1110 | -. | |
| BioCyc | CPNE115711:CP1110-MONOMER | -.1 | |
| BioCyc | CPNE115713:CPN0762-MONOMER | -.1 | |
| BioCyc | CPNE138677:CPJ0762-MONOMER | -.1 | |
| BioCyc | CPNE182082:CPB0790-MONOMER | -.1 | |
| HAMAP | MF_00268 | - | 1. |
| InterPro | IPR003593 | AAA_ATPase. | |
| InterPro | IPR001553 | RecA_bac. | |
| Pfam | PF00154 | RecA | 1. |
| PRINTS | PR00142 | RECA. | |
| ProDom | PD000229 | RecA | 1. |
| SMART | SM00382 | AAA | 1. |
| TIGRFAMs | TIGR02012 | tigrfam_recA | 1. |
| PROSITE | PS00321 | RECA_1 | 1. |
| PROSITE | PS50162 | RECA_2 | 1. |
| PROSITE | PS50163 | RECA_3 | 1. |
Keywords:
ATP-binding; Complete proteome; DNA damage; DNA recombination; DNA repair; DNA-binding; Nucleotide-binding; SOS response.
References:
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CWL029;
RX MEDLINE=99206606; PubMed=10192388; DOI=10.1038/7716;
RA Kalman S., Mitchell W.P., Marathe R., Lammel C.J., Fan J., Hyman R.W.,
RA Olinger L., Grimwood J., Davis R.W., Stephens R.S.;
RT "Comparative genomes of Chlamydia pneumoniae and C. trachomatis.";
RL Nat. Genet. 21:385-389(1999).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=AR39;
RX MEDLINE=20150255; PubMed=10684935; DOI=10.1093/nar/28.6.1397;
RA Read T.D., Brunham R.C., Shen C., Gill S.R., Heidelberg J.F.,
RA White O., Hickey E.K., Peterson J.D., Utterback T.R., Berry K.J.,
RA Bass S., Linher K.D., Weidman J.F., Khouri H.M., Craven B., Bowman C.,
RA Dodson R.J., Gwinn M.L., Nelson W.C., DeBoy R.T., Kolonay J.F.,
RA McClarty G., Salzberg S.L., Eisen J.A., Fraser C.M.;
RT "Genome sequences of Chlamydia trachomatis MoPn and Chlamydia
RT pneumoniae AR39.";
RL Nucleic Acids Res. 28:1397-1406(2000).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=J138;
RX MEDLINE=20330349; PubMed=10871362; DOI=10.1093/nar/28.12.2311;
RA Shirai M., Hirakawa H., Kimoto M., Tabuchi M., Kishi F., Ouchi K.,
RA Shiba T., Ishii K., Hattori M., Kuhara S., Nakazawa T.;
RT "Comparison of whole genome sequences of Chlamydia pneumoniae J138
RT from Japan and CWL029 from USA.";
RL Nucleic Acids Res. 28:2311-2314(2000).
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=TW-183;
RA Geng M.M., Schuhmacher A., Muehldorfer I., Bensch K.W., Schaefer K.P.,
RA Schneider S., Pohl T., Essig A., Marre R., Melchers K.;
RT "The genome sequence of Chlamydia pneumoniae TW183 and comparison with
RT other Chlamydia strains based on whole genome sequence analysis.";
RL Submitted (MAY-2002) to the EMBL/GenBank/DDBJ databases.
Feature:
CHAIN 1 353 Protein recA.
/FTId=PRO_0000122685.
NP_BIND 67 74 ATP (By similarity).
CONFLICT 319 319 E -> K (in Ref. 4).
Comments:
-!- FUNCTION: Can catalyze the hydrolysis of ATP in the presence of
single-stranded DNA, the ATP-dependent uptake of single-stranded
DNA by duplex DNA, and the ATP-dependent hybridization of
homologous single-stranded DNAs. It interacts with lexA causing
its activation and leading to its autocatalytic cleavage.
-!- SUBCELLULAR LOCATION: Cytoplasm (By similarity).
-!- SIMILARITY: Belongs to the recA family.
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Sequence length: 353
MNLPDRKKAL EAAVAYIEKQ FGAGSIMSLG RHSATHEIST IKTGALSLDL ALGIHGVPKG
RVIEIFGPES SGKTTLATHI VANAQKMGGV AAYIDAEHAL DPSYASLIGV NIDDLMISQP
DCGEDALSIA ELLARSGAVD VIVIDSVAAL VPKSELEGDI GDVHVGLQAR MMSQALRKLT
ATLSRSQTCA VFINQIREKI GVSFGNPETT TGGRALKFYS SIRLDIRRIG SIKGSDNSDI
GNRIKVKVAK NKLAPPFRIA EFDILFNEGI SSAGCILDLA VEYNIIEKKG SWFNYQEKKL
GQGREFVREE LKRNRKLFEE IEKRIYDVIA ANKTPSVHAN ETPQEVPAQT VEA