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Description:
DNA repair protein radA homolog (DNA repair protein sms homolog).
Molecular weight: 49557
View which proteins in this organism that is involved with DNA Repair;
classified after biological processes (using data from the GOA project):
DNA repair( GO:0006281 )
Important dates:
11-JAN-2001, integrated into UniProtKB/Swiss-Prot.
01-MAY-1999, sequence version 1.
07-MAR-2006, entry version 38.
Phylogenetic order:
Bacteria Proteobacteria Epsilonproteobacteria Campylobacterales Helicobacteraceae Helicobacter.
To calculate the pI (Isoelectric point - the pH where a protein has a neutral charge),
go to this page and enter the protein ID (e.g 3MG_ECOLI): http://us.expasy.org/tools/pi_tool.html
Links to references in other databases for protein RADA_HELPJ:
| Database | Pointer | Add. info#1 | Add. info#2 |
| EMBL | AE001459 | AAD05792.1 | - |
| PIR | D71960 | D71960. | |
| GenomeReviews | AE001439_GR | JHP0209.1 | |
| BioCyc | HPYL85963:JHP0209-MONOMER | -.1 | |
| InterPro | IPR003593 | AAA_ATPase. | |
| InterPro | IPR001984 | Peptidase_S16. | |
| InterPro | IPR004504 | RadA. | |
| InterPro | IPR001553 | RecA_bac. | |
| PRINTS | PR01874 | DNAREPAIRADA. | |
| PRINTS | PR00830 | ENDOLAPTASE. | |
| SMART | SM00382 | AAA | 1. |
| TIGRFAMs | TIGR00416 | sms | 1. |
| PROSITE | PS50162 | RECA_2 | 1. |
Keywords:
ATP-binding; Complete proteome; DNA damage; DNA repair; DNA-binding; Metal-binding; Nucleotide-binding; Zinc; Zinc-finger.
References:
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX MEDLINE=99120557; PubMed=9923682; DOI=10.1038/16495;
RA Alm R.A., Ling L.-S.L., Moir D.T., King B.L., Brown E.D., Doig P.C.,
RA Smith D.R., Noonan B., Guild B.C., deJonge B.L., Carmel G.,
RA Tummino P.J., Caruso A., Uria-Nickelsen M., Mills D.M., Ives C.,
RA Gibson R., Merberg D., Mills S.D., Jiang Q., Taylor D.E., Vovis G.F.,
RA Trust T.J.;
RT "Genomic sequence comparison of two unrelated isolates of the human
RT gastric pathogen Helicobacter pylori.";
RL Nature 397:176-180(1999).
Feature:
CHAIN 1 448 DNA repair protein radA homolog.
/FTId=PRO_0000187929.
ZN_FING 10 27 C4-type (Potential).
NP_BIND 96 103 ATP (Potential).
Comments:
-!- FUNCTION: May play a role in the repair of endogenous alkylation
damage (By similarity).
-!- SIMILARITY: Belongs to the recA family. RadA subfamily.
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Sequence length: 448
MAKKTSLFEC QHCGFTSPKW LGKCVQCNAW ESFIELNQTQ KEVLNALKKP LPQVQKSVSI
AEIEHEEVIK FSSTQSELDI VLGGGIAKGG LYLVGGSPGV GKSTLLLKVA SGLAKNQQKV
LYVSGEESLS QIKMRATRLD CIEEELYLLN EINWPVIKAN MESENYFACV IDSIQTLYSP
EISSAPGSIS QVREITFELM RLAKTRDIAI FIIGHITKEG SIAGPRVLEH MVDSVLYFEG
DPSRELRILR SFKNRFGPTS EIGLFEMKEQ GLVSAKEASS LFFSKEEPME GSAITITLEG
SRALILEIQA LVSECSFGAP KRLANGFDTN RLNMLIALLE KKLEIPLNRH DVFINVSGGI
KISEPACDLA VIASILSSFK NRKIDNKTAF LGEVSLNGRI LEAPNLNARL KEMENYGFLK
AILPKKPSQK TSIKCYEANV VGKIVEWM