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Description:
Single-stranded DNA-binding protein (SSB) (Helix-destabilizingprotein).
Molecular weight: 20382
View which proteins in this organism that is involved with DNA Repair;
classified after biological processes (using data from the GOA project):
DNA repair( GO:0006281 )
Important dates:
01-DEC-2000, integrated into UniProtKB/Swiss-Prot.
01-MAY-1999, sequence version 1.
07-MAR-2006, entry version 33.
Phylogenetic order:
Bacteria Proteobacteria Epsilonproteobacteria Campylobacterales Helicobacteraceae Helicobacter.
To calculate the pI (Isoelectric point - the pH where a protein has a neutral charge),
go to this page and enter the protein ID (e.g 3MG_ECOLI): http://us.expasy.org/tools/pi_tool.html
Links to references in other databases for protein SSB_HELPJ:
| Database | Pointer | Add. info#1 | Add. info#2 |
| EMBL | AE001544 | AAD06751.1 | - |
| PIR | E71840 | E71840. | |
| HSSP | P02339 | 1EYG | |
| GenomeReviews | AE001439_GR | JHP1166.1 | |
| BioCyc | HPYL85963:JHP1166-MONOMER | -.1 | |
| InterPro | IPR012340 | OB_NA_bd_sub. | |
| InterPro | IPR011344 | Single_strand_bd. | |
| InterPro | IPR000424 | SSB_primosomal_n. | |
| InterPro | IPR010913 | ssDNA_bd. | |
| Pfam | PF00436 | SSB | 1. |
| TIGRFAMs | TIGR00621 | ssb | 1. |
| PROSITE | PS50935 | SSB | 1. |
Keywords:
Complete proteome; DNA damage; DNA repair; DNA replication; DNA-binding.
References:
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX MEDLINE=99120557; PubMed=9923682; DOI=10.1038/16495;
RA Alm R.A., Ling L.-S.L., Moir D.T., King B.L., Brown E.D., Doig P.C.,
RA Smith D.R., Noonan B., Guild B.C., deJonge B.L., Carmel G.,
RA Tummino P.J., Caruso A., Uria-Nickelsen M., Mills D.M., Ives C.,
RA Gibson R., Merberg D., Mills S.D., Jiang Q., Taylor D.E., Vovis G.F.,
RA Trust T.J.;
RT "Genomic sequence comparison of two unrelated isolates of the human
RT gastric pathogen Helicobacter pylori.";
RL Nature 397:176-180(1999).
Feature:
CHAIN 1 181 Single-stranded DNA-binding protein.
/FTId=PRO_0000096051.
DOMAIN 1 106 SSB.
Comments:
-!- FUNCTION: This protein is essential for replication of the
chromosome. It is also involved in DNA recombination and repair
(By similarity).
-!- SIMILARITY: Contains 1 SSB domain.
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Sequence length: 181
MFNKVIMVGR LTRNVELKYL PSGSAAATIG LATSRRFKKQ DGTLGEEVCF IDARLFGRTA
EIANQYLSKG SSVLIEGRLT YESWMDQTGK KNSRHTITAD SLQFMDKKSD NPQANSMQDS
MTHENFNNAY PTNYNAPSQD PFSQAQSYPQ NAYTKENSQA QPSKYQNSVP EINIDEEEIP
F