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Description:
DNA replication and repair protein recF.
Molecular weight: 42726
View which proteins in this organism that is involved with DNA Repair;
classified after biological processes (using data from the GOA project):
DNA repair( GO:0006281 )
Important dates:
04-MAY-2001, integrated into UniProtKB/Swiss-Prot.
01-MAY-2000, sequence version 1.
07-MAR-2006, entry version 32.
Phylogenetic order:
Bacteria Firmicutes Bacillales Bacillaceae Bacillus.
To calculate the pI (Isoelectric point - the pH where a protein has a neutral charge),
go to this page and enter the protein ID (e.g 3MG_ECOLI): http://us.expasy.org/tools/pi_tool.html
Links to references in other databases for protein RECF_BACHD:
| Database | Pointer | Add. info#1 | Add. info#2 |
| EMBL | AB013492 | BAA82688.1 | - |
| EMBL | BA000004 | BAB03723.1 | - |
| PIR | D83650 | D83650. | |
| GenomeReviews | BA000004_GR | BH0004.1 | |
| BioCyc | BHAL86665:BH0004-MONOMER | -.1 | |
| HAMAP | MF_00365 | - | 1. |
| InterPro | IPR001238 | RecF. | |
| InterPro | IPR003395 | SMC_N. | |
| Pfam | PF02463 | SMC_N | 1. |
| TIGRFAMs | TIGR00611 | recf | 1. |
| PROSITE | PS00617 | RECF_1 | 1. |
| PROSITE | PS00618 | RECF_2 | 1. |
Keywords:
ATP-binding; Complete proteome; DNA damage; DNA repair; DNA replication; DNA-binding; Nucleotide-binding; SOS response.
References:
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC STRAIN=C-125 / JCM 9153;
RX MEDLINE=99356711; PubMed=10427704;
RA Takami H., Masui N., Nakasone K., Horikoshi K.;
RT "Replication origin region of the chromosome of alkaliphilic Bacillus
RT halodurans C-125.";
RL Biosci. Biotechnol. Biochem. 63:1134-1137(1999).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=C-125 / JCM 9153;
RX MEDLINE=20512582; PubMed=11058132; DOI=10.1093/nar/28.21.4317;
RA Takami H., Nakasone K., Takaki Y., Maeno G., Sasaki R., Masui N.,
RA Fuji F., Hirama C., Nakamura Y., Ogasawara N., Kuhara S.,
RA Horikoshi K.;
RT "Complete genome sequence of the alkaliphilic bacterium Bacillus
RT halodurans and genomic sequence comparison with Bacillus subtilis.";
RL Nucleic Acids Res. 28:4317-4331(2000).
Feature:
CHAIN 1 371 DNA replication and repair protein recF.
/FTId=PRO_0000196397.
NP_BIND 30 37 ATP (Potential).
Comments:
-!- FUNCTION: The recF protein is involved in DNA metabolism; it is
required for DNA replication and normal SOS inducibility. RecF
binds preferentially to single-stranded, linear DNA. It also seems
to bind ATP (By similarity).
-!- SUBCELLULAR LOCATION: Cytoplasm (By similarity).
-!- SIMILARITY: Belongs to the recF family.
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Sequence length: 371
MHIERLTLKQ FRNYDELDVS FEPNVNVIIG ENAQGKTNVI EAIYFLALAK SHRTARDKEL
IQWEAPFARI EGAFQKQNGP LSLHVVLSGK GKKVKVNGLE QRRLSDYIGA VNVVMFGPED
LNLVKGSPQI RRRFLDMELG QMSPVYLHQL AMYQKILLQR NHLLKQLFGK ANSDPMLDVL
TDQLIEVAVE VTKKRFEFIQ LLQRWAEEIH QAISRGKEKL VITYEPSVHV SEQLNLSKLR
EGFYQAYEQK KERERQRGTT LFGPHRDDLV FFVNDKDVQT YGSQGQQRTT ALSLKLAEIE
LMKETVGDYP ILLLDDVLSE LDDYRQSHLL HAIQHRVQTF VTTTNVDGID HQTLQEATIY
EVEQGSLKKK G