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Protein data for EX5B_BUCAP:

Description:
Exodeoxyribonuclease V beta chain (EC 3.1.11.5).

Molecular weight: 1410

View which proteins in this organism that is involved with DNA Repair;
classified after biological processes (using data from the GOA project):
DNA repair( GO:0006281 )


Important dates:
08-NOV-2002, integrated into UniProtKB/Swiss-Prot.
01-OCT-2002, sequence version 1.
07-MAR-2006, entry version 23.

Phylogenetic order:
Bacteria Proteobacteria Gammaproteobacteria Enterobacteriales Enterobacteriaceae Buchnera.

To calculate the pI (Isoelectric point - the pH where a protein has a neutral charge),
go to this page and enter the protein ID (e.g 3MG_ECOLI): http://us.expasy.org/tools/pi_tool.html

Links to references in other databases for protein EX5B_BUCAP:

DatabasePointerAdd. info#1Add. info#2
EMBLAE014120AAM67982.1-
GenomeReviewsAE013218_GRBUsg439.1
InterProIPR004586RecB.
InterProIPR000212UvrD-helicase.
PANTHERPTHR11070UvrD-helicase.13.
PfamPF00580UvrD-helicase1.
TIGRFAMsTIGR00609recB1.

General information about the databases mentioned above

Keywords:
ATP-binding; Complete proteome; DNA damage; DNA repair; Endonuclease; Exonuclease; Helicase; Hydrolase; Nuclease; Nucleotide-binding.

References:
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX MEDLINE=22084549; PubMed=12089438; DOI=10.1126/science.1071278;
RA Tamas I., Klasson L., Canbaeck B., Naeslund A.K., Eriksson A.-S.,
RA Wernegreen J.J., Sandstroem J.P., Moran N.A., Andersson S.G.E.;
RT "50 million years of genomic stasis in endosymbiotic bacteria.";
RL Science 296:2376-2379(2002).

Feature:
CHAIN 1 1179 Exodeoxyribonuclease V beta chain.
/FTId=PRO_0000102041.
NP_BIND 39 46 ATP (Potential).

Comments:
-!- FUNCTION: Required for efficient DNA repair; it catalyzes the
unwinding of double-stranded DNA and the cleavage of single-
stranded DNA and it stimulates local genetic recombination. All of
these activities require concomitant hydrolysis of ATP (By
similarity).
-!- CATALYTIC ACTIVITY: Exonucleolytic cleavage (in the presence of
ATP) in either 5'- to 3'- or 3'- to 5'-direction to yield 5'-
phosphooligonucleotides.
-!- SUBUNIT: Consist of three subunits; recB, recC and recD (By
similarity).
-!- SIMILARITY: Belongs to the helicase family. UvrD subfamily.
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Sequence length: 1179

     MVYSDTKTSK KIKKYKINIM KKKLNIFQIP LKGIHLIEAS AGTGKTSTIA FLYLRLLLGL
     EKNKENIRKL SVKEILVVTF TNAAKEELYI RIKKSIKELH LSCIKKKSKD PIFQSFLTKI
     KNFDEAIHIL EDAKININNA AIYTIHGFCQ DVLENNTLIS NREIIENESF LYLQATQDFW
     RYFFYNLPKK IIKIIYEEYR SPEDLLREIK PILKVNSSIN FKKKFDKKET LITFHEKIIN
     KINIFKQKWL NYNLIILKII NQLKVNKKIY SNFNILKWKK KITEWAESET KNYKMPICLK
     YFSETSIEKN IKNYNFKKHI FFEEIDKILK KNFSLKNIIL FYAIKNIPKF VKREKEKKLL
     LGFNDLLKIL LKNIKKEESL REIIIKQYPV ALIDEFQDTN IQQYQIFNTL YKNKKTALFL
     VGDPKQSIYS FRGADIFSYL HAKFKIKNYY YLDTNWRSSK NICKAINYLF SKNKNPFYFK
     NIPFEPILSS SKNLNMKFKI KEKNQTAISF FFQKKEEVNI EEYRDWIAKQ CANEISYWLT
     CSKKGEAIIS DGSQERILTE KDIVILVRNR TEAQIIKESL KKVNILSKYS SPYESVFKTF
     DALELLSILK SILDPTDINL LKKSILTHIL NKIAFQKIKE NSKTKISHFL IQKLYEYNDK
     WKTIGIFYTI KTMILEYQKY ANNFEMYKNQ QRNINFLHIA ELLQEKSQNC YKENSLMRWF
     EKKILEKNNI SENEYIKNFA ESKIIRIITI HKSKGLEYPI VWIPFIVDFN VSKSYFYHEK
     KTLKIFFDNN KSSETLKKSD EERLAEDLRF LYVALTRSIY HCSIGISYLV KKRKKNKKSS
     DIHKSSLGYI IQNGKCMNYK ELLYELKILN KKLYIEVKYQ AMNCKSLTIK KDDLYILSQP
     QFLLKEIKLY SQITSFTKIK QENKHFNNIQ YNNIESYFFK EKDKKKTIHN FPHGNKAGIF
     IHYILKTIKF NNTFNIDWFY TILKKYEFSE KWAKTLMFWI NNILNFKINN LNITLSSLKK
     TQYIKELEFF LPIKNTLYCE DLNQIIQSID LISSISQKIF FNPVIGILKG FIDLVFIFNK
     KYYILDYKCN YLGNNDNCYS SKNIKKEIIK NRYDIQYQLY TLALHQYLKK KVKQYHYKTH
     FGGVFYLFLR GINVKDSIFY ILPDYLLIKK LTKLILQKK

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