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Description:
Exodeoxyribonuclease V gamma chain (EC 3.1.11.5).
Molecular weight: 1276
View which proteins in this organism that is involved with DNA Repair;
classified after biological processes (using data from the GOA project):
DNA repair( GO:0006281 )
Important dates:
08-NOV-2002, integrated into UniProtKB/Swiss-Prot.
01-OCT-2002, sequence version 1.
07-MAR-2006, entry version 22.
Phylogenetic order:
Bacteria Proteobacteria Gammaproteobacteria Enterobacteriales Enterobacteriaceae Buchnera.
To calculate the pI (Isoelectric point - the pH where a protein has a neutral charge),
go to this page and enter the protein ID (e.g 3MG_ECOLI): http://us.expasy.org/tools/pi_tool.html
Links to references in other databases for protein EX5C_BUCAP:
| Database | Pointer | Add. info#1 | Add. info#2 |
| EMBL | AE014120 | AAM67981.1 | - |
| GenomeReviews | AE013218_GR | BUsg438.1 | |
| InterPro | IPR006697 | RecC. | |
| Pfam | PF04257 | Exonuc_V_gamma | 1. |
| TIGRFAMs | TIGR01450 | recC | 1. |
Keywords:
ATP-binding; Complete proteome; DNA damage; DNA repair; Endonuclease; Exonuclease; Helicase; Hydrolase; Nuclease; Nucleotide-binding.
References:
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX MEDLINE=22084549; PubMed=12089438; DOI=10.1126/science.1071278;
RA Tamas I., Klasson L., Canbaeck B., Naeslund A.K., Eriksson A.-S.,
RA Wernegreen J.J., Sandstroem J.P., Moran N.A., Andersson S.G.E.;
RT "50 million years of genomic stasis in endosymbiotic bacteria.";
RL Science 296:2376-2379(2002).
Feature:
CHAIN 1 1061 Exodeoxyribonuclease V gamma chain.
/FTId=PRO_0000087118.
Comments:
-!- FUNCTION: Exhibits a wide variety of catalytic activities
including ATP-dependent exonuclease, ATP-stimulated endonuclease,
ATP-dependent helicase and DNA-dependent ATPase activities (By
similarity).
-!- CATALYTIC ACTIVITY: Exonucleolytic cleavage (in the presence of
ATP) in either 5'- to 3'- or 3'- to 5'-direction to yield 5'-
phosphooligonucleotides.
-!- SUBUNIT: Consist of three subunits; recB, recC and recD (By
similarity).
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Sequence length: 1061
MFFVYRSNQI DILFTKICKI IKKKPLLNIF EREIIIHDNE ILFQNLNTFI ANHTGIAADF
KLIYPNVFIW KLFKQVFSDI QLNNIFSRST ITWKIMKIIE ENDFCKFVQK KDKIMKKFEF
SFLMSHLYQQ YILYRPNWIN MWEKNKKNTL KIEKKDEWQA KLWIKIILYT EKLQQSKWHF
SNLFKKFKTL KKIEHIKFPK RIFIIYSISL NPKYMEIFKK ISTYTDIYFL SINACEKKIF
HISFAKNYVV QKNNLLMNLS EKYEKFYFLF FKKFKKIKYN NFFQKNNSNN LLNIVKNDFL
NFKEKENLLK KNSFLLKDNS ISINICCDKK HEIEVLYNKL LSFFNEDSKL KPSDIVITSF
SLNTYIIYIN SIFKSKNKKE KIPFYISKKH SDKIEKILFI FNKILNLPNI RCNNEEILDL
IEIQDIRDKF DISEEEINIL YEWIEKANIR WGLHENEKQK NNLIFIKKNQ NTWFYGIKKL
LISHAINEEE EVWNNVLSCT SINTSRTELI GKLINFIKVL DQWRDKLFFS KKIKSWRPLF
LCFIKDFFYK NEKIRDSIDI INKTWTKMID DATLSNYEKK IPISILKKKF SHIMNNFSEK
KFLPGVINFC HPSLVCYIPF KIKCIIGAEY QEIPKKKLSS FNLIDKYPLT SDLHICKENY
IFLQNFISTQ ETLYISYVGH SLKNNNKVRS SILIDQLLNH ITSNFYVSEH HDYKNNKKEI
FEHICKKHKK ENLYEKKQVN KINLNTLQKT KKINQEIYNK IFSIKNRIIS TSTQISLKSL
ISFWKNPIRY FFNYTLNIKL KIAKRNIITE PFSINLFDDF KISNIIFKKI LNNESIKDEF
KKIILSGILP YGHFGSILLK EKKKEIENIV KAIYKYRISS PKKENFDIKI EKYNINGCLD
EIQNTGLLRW KLGTINYRDR ISLWLEHLIY CILGGTGESK IIGYKKNFFS FYPLSSHLAY
NYLFTYIEGY MKGMKNPLLL IKSGSNWFDK VYDKKNDCIK KNDDIKRKAY KILYHTWMGN
EYITGEKEDL YIQQIISELN VKKICKISQK WFTPILKHQK K